Synthesis and spectral investigations of a new dyad with spiropyran and fluorescein units: Toward information processing at the single molecular level
Synthesis and spectral investigations of a new dyad with spiropyran and fluorescein units: Toward information processing at the single molecular level
复制标题
DOI：
10.1021/jo034243w
复制
发表时间：
2003-07-11
影响因子：
3.6
通讯作者：
Zhu, DB
中科院分区：
文献类型：
--
作者：
Guo, XF;Zhang, XF;Zhu, DB
合成并表征了一种新的二联体1，其中两个螺吡喃单元作为光致变色受体，一个荧光素单元作为荧光供体。外部输入（紫外光，可见光和质子）诱导结构的可逆变化，并伴随着，由于存在两个螺吡喃单元的二分体I的吸收光谱。只有二分体1中螺吡喃单元的ME形式的吸收光谱与荧光素单元的荧光光谱具有大的光谱重叠。因此，二联体1的荧光强度通过光致变色螺吡喃单元的三种状态之间的可逆转换以及ME形式与荧光素单元之间的荧光共振能量转移（FRET）来调制。基于二分体1可以“读出”三个外部输入信号（紫外光、可见光、紫外线和质子）和“写入”兼容的特定输出信号（荧光强度）的事实，这里描述的二分体1可以被认为是执行具有一个或和一个与互连逻辑门的集成电路功能。目前的结果表明，一个有效的策略，在单分子水平上阐述和传递信息。
A new dyad 1 with two spiropyran units as the photochromic acceptors and one fluorescein unit as the fluorescent donor was synthesized and characterized. External inputs (ultraviolet light, visible light, and proton) induce the reversible changes of the structure and, concomitantly, the absorption spectrum of dyad I due to the presence of two spiropyran units. Only the absorption spectrum of the ME form of the spiropyran units in dyad 1 has large spectral overlap with the fluorescence spectrum of the fluorescein unit. Thus, the fluorescence intensity of dyad 1 is modulated by reversible conversion among the three states of the photochromic spiropyran units and the fluorescence resonance energy transfer (FRET) between the ME form and the fluorescein unit. Based on the fact that dyad 1 could "read out" three external input signals (ultraviolet light, visible ligh,t and proton) and "write" a compatible specific output signal (fluorescence intensity), dyad 1 described here can be considered to perform an integrated circuit function with one OR and one AND interconnected logic gates. The present results demonstrate an efficient strategy for elaborating and transmitting information at the single molecular level.