Prospective study of short‐term peginterferon‐α‐2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy

Prospective study of short‐term peginterferon‐α‐2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy
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对开始干扰素治疗后 2 周出现病毒学应答的患者进行短期聚乙二醇干扰素-α-2a 单药治疗的前瞻性研究

DOI:
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发表时间:
2008
影响因子:
4.1
通讯作者:
K. Chayama
K. Chayama
中科院分区:
医学3区
文献类型:
--
作者:
S. Jeong;Y. Kawakami;M. Kitamoto;Hiroto Ishihara;K. Tsuji;S. Aimitsu;H. Kawakami;K. Uka;S. Takaki;Hideaki Kodama;K. Waki;M. Imamura;H. Aikata;Shoichi Takahashi;K. Chayama

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背景与目的: 长期干扰素治疗能有效消除丙型肝炎病毒。然而,它带来了不良影响和生活质量下降的风险。为了评估短期干扰素疗法是否有效地消除丙型肝炎病毒,我们进行了一项为期8周或24周的聚乙二醇化干扰素-α-2a治疗的前瞻性先导研究。
Background and Aims:  Long‐term interferon (IFN) therapy is effective in eliminating hepatitis C virus (HCV). However, it carries the risk of adverse effects and reduced quality of life. To assess whether short‐term IFN therapy effectively eliminates HCV, we performed a prospective pilot study of pegylated (peg)IFN‐α‐2a therapy for 8 or 24 weeks.
DOI: 10.1053/gast.2002.35950
发表时间: 2002-10-01
期刊: GASTROENTEROLOGY
影响因子: 29.4
作者:
McHutchison, JG;Manns, M;Albrecht, JK
通讯作者: Albrecht, JK