Advances in quantitative perfusion SPECT imaging

Advances in quantitative perfusion SPECT imaging
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DOI:
10.1016/j.nuclcard.2003.10.007
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发表时间:
2004-01-01
影响因子:
2.4
通讯作者:
Corbett, JR
Corbett, JR
中科院分区:
医学3区
文献类型:
--
作者:
Ficaro, EP;Corbett, JR

文献摘要

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心肌灌注单光子发射计算机断层成像(SPECT)的定量软件在过去的25年中有了显著的进步。与其他用于检测冠状动脉疾病的高分辨率非侵入性成像方法相比,SPECT灌注成像定量工具的强度和可用性在许多方面为核心脏病学提供了竞争优势。本报告的目的是回顾过去25年来心脏SPECT定量诊断软件的进展。20世纪80年代结束的时间段(“过去”)见证了核心脏病学的起源,发展了平面铊201成像和无心电门控的SPECT灌注成像。从1990年到现在,门控SPECT成像的发展同时提供了灌注和功能信息,衰减校正SPECT则提供了更好的灌注信息。该报告最后对未来进行了展望,混合型多模式成像系统可能会在单一成像过程中以前所未有的精度提供全面的非侵入性评估。
Quantitative software for myocardial perfusion single photon emission computed tomography (SPECT) has advanced significantly over the last 25 years. The strength and availability of quantitative tools for perfusion SPECT have in many ways provided a competitive advantage to nuclear cardiology compared with other higher-resolution noninvasive imaging modalities for the detection of coronary artery disease. The purpose of this report is to review the advances in quantitative diagnostic software for cardiac SPECT over the past 25 years. The time period ending with the 1980s ("the past") saw the origins of nuclear cardiology with the development of planar thallium 201 imaging and perfusion SPECT imaging without electrocardiographic gating. The period from 1990 to the present saw the development of gated SPECT imaging providing both perfusion and functional information and attenuation correction SPECT with improved perfusion information. The report concludes with a look into the future, where hybrid multimodality imaging systems may provide a comprehensive noninvasive evaluation with previously unmatched accuracy in a single imaging session.