Crystal structures and antimicrobial activities of copper(II) complexes of fluorine-containing thioureido ligands
Crystal structures and antimicrobial activities of copper(II) complexes of fluorine-containing thioureido ligands
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含氟硫脲配体铜(II)配合物的晶体结构和抗菌活性
DOI：
10.1016/j.ica.2013.06.029
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发表时间：
2013-08-24
影响因子：
2.8
通讯作者：
Li, Mengying
中科院分区：
文献类型：
--
作者：
Liu, Huanhuan;Yang, Wen;Li, Mengying
合成了N-4-氟苯甲酰哌啶-1-硫代亚胺酯(L1(-))、N-2-氟苯甲酰哌啶-1-硫代亚胺酯(L2(-))和2-氟苯甲酸酯(L3(-))的Cu(II)配合物，并通过元素分析、傅里叶变换红外(FT-IR)、紫外(UV)和荧光光谱方法对其进行了表征。通过X射线衍射法测定了[Cu(L1)(2)]、[Cu(L2)(2)]和[Cu-2(L3)(4)(DMF)(2)]（DMF：N,N-二甲基甲酰胺）的晶体结构。与相应的配体进行比较，研究了复合物对细菌（大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌、铜绿假单胞菌和希瓦氏菌）和真菌（灰葡萄孢、木霉属、漆斑菌属和黄萎病菌属）的抗菌活性。实验表明，该配合物比相应的配体具有更强的抗菌和抗真菌活性。 (C) 2013 作者。由 Elsevier B.V. 出版。保留所有权利。
Cu(II) complexes with N-4-fluorobenzoylpiperidine-1-carbothioimidate (L1(-)), N-2-fluorobenzoylpiperidine-1-carbothioimidate (L2(-)) and 2-fluorobenzoate (L3(-)) have been synthesized and characterized by elemental analysis, Fourier Transform infrared (FT-IR), Ultraviolet (UV) and fluorescence spectroscopy methods. The crystal structures of [Cu(L1)(2)], [Cu(L2)(2)] and [Cu-2(L3)(4)(DMF)(2)] (DMF: N,N-dimethylformamide) have been determined by X-ray diffraction method. The antimicrobial activities of the complexes against the bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Shewanella sp.) and the fungi (Botrytis cinerea, Trichoderma spp., Myrothecium and Verticillium spp.) have been investigated comparing with the corresponding ligands. The experiments showed that the complexes had the stronger antibacterial and antifungal activities than the corresponding ligands had. (C) 2013 The Authors. Published by Elsevier B.V. All rights reserved.