Hemodynamic effects of pressure-volume relation in the atrial contraction model on the total artificial heart using centrifugal blood pumps
Hemodynamic effects of pressure-volume relation in the atrial contraction model on the total artificial heart using centrifugal blood pumps
复制标题
心房收缩模型中压力-容积关系对离心血泵全人工心脏血流动力学的影响
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
T. Yambe
中科院分区：
文献类型：
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作者：
T. Shiga;Takehito Kuroda;Y. Tsuboko;H. Miura;Y. Shiraishi;T. Yambe
离心泵型全人工心脏心房收缩的血流动力学效应尚不清楚。在这项研究中，我们在模拟模型中模拟了心房收缩。在模拟心房模型中，在较高压力的驾驶条件下，心房收缩的负荷增加。基于这些发现，我们使用成年山羊检测了动物的心房收缩。测量前安装离心式脑室辅助装置(VADs)，然后夹闭双侧脑室。在全人工心脏(TAH)循环支持模型条件下，测量不含心室收缩功能的血流动力学数据，以了解心房收缩对血流动力学的影响。我们可以通过泵的转速和电压来估计心率。我们有可能通过控制心输出量来调节自主神经反应。
Hemodynamic effects of atrial contraction with centrifugal pump type total artificial heart is unknown. In this study, we simulated an atrial contraction in a mock model. By the driving condition with higher pressure in the mock atrial model, the load during atrial contraction increased. Based on these findings, we examined atrial contraction in the animal using adult goats. Prior to the measurement, we installed a centrifugal-type ventricular assist device (VADs), and then clamped both ventricles. We measured the hemodynamic data without ventricular contractile functions in order to obtain the effect of atrial contraction on hemodynamics under the condition of the total artificial heart (TAH) circulatory support model. We could estimate the heart rate by revolution number and voltage of pumps. There might be a possibility that we could regulate autonomic nervous response with the control of cardiac output.
影响因子：
158.5
作者：
Rose, EA;Gelijns, AC;Meier, P
通讯作者：
Meier, P