Participation of the insula in language revisited: A meta-analytic connectivity study
Participation of the insula in language revisited: A meta-analytic connectivity study
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DOI：
10.1016/j.jneuroling.2014.02.001
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发表时间：
2014-05-01
影响因子：
2
通讯作者：
Rosselli, Monica
中科院分区：
文献类型：
--
作者：
Ardila, Alfredo;Bernal, Byron;Rosselli, Monica
尽管它位于人类语言区的中心，但它在语言中的具体作用还没有得到充分的理解。左脑与多种言语/语言功能有关，包括发音规划，语言重复能力和语音识别。为了进一步了解大脑皮层在语言中的作用，开发了一种使用激活似然估计（ALE）技术的元分析连接性研究。利用BrainMap功能数据库，共筛选出26篇论文，涉及39个范式，共522名被试。发现了13个不同的激活簇;这些联系不仅涉及语言产生的领域，（如布罗卡区）和语言理解（如韦尼克区），但也涉及语言重复的区域（如缘上回）和其他语言功能，例如左前额叶的BA 9（参与复杂的语言过程）和BA 37（参与词汇语义联想）。总之，正如世纪提出的那样，大脑皮层代表了语言处理的一个核心区域。(C)2014爱思唯尔有限公司版权所有。
Despite the insula's location in the epicenter of the human language area, its specific role in language is not sufficiently understood. The left insula has been related to a diversity of speech/language functions, including articulatory planning, language repetition ability, and phonological recognition. To further our understanding of the role of the insula in language, a meta-analytic connectivity study using the Activation Likelihood Estimation (ALE) technique was developed. By means of the BrainMap functional database, 26 papers corresponding to 39 paradigms, and including 522 participants were selected. Thirteen different activation clusters were found; insula connections included not only areas involved in language production (such as the Broca's area) and language understanding (such as the Wernicke's area), but also areas involved in language repetition (such as the supramarginal gyrus) and other linguistic functions, such as BA9 in the left prefrontal lobe (involved in complex language processes) and BA37 (involved in lexico-semantic associations). In conclusion, the insula represents a core area in language processing, as it was suggested during the 19th century. (C) 2014 Elsevier Ltd. All rights reserved.