A Semiparametric Bayesian Approach to Dropout in Longitudinal Studies with Auxiliary Covariates.
A Semiparametric Bayesian Approach to Dropout in Longitudinal Studies with Auxiliary Covariates.
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DOI：
10.1080/10618600.2019.1617159
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Müller P
中科院分区：
文献类型：
--
作者：
Zhou T;Daniels MJ;Müller P
We develop a semiparametric Bayesian approach to missing outcome data in longitudinal studies in the presence of auxiliary covariates. We consider a joint model for the full data response, missingness and auxiliary covariates. We include auxiliary covariates to “move” the missingness “closer” to missing at random (MAR). In particular, we specify a semiparametric Bayesian model for the observed data via Gaussian process priors and Bayesian additive regression trees. These model specifications allow us to capture non-linear and non-additive effects, in contrast to existing parametric methods. We then separately specify the conditional distribution of the missing data response given the observed data response, missingness and auxiliary covariates (i.e. the extrapolation distribution) using identifying restrictions. We introduce meaningful sensitivity parameters that allow for a simple sensitivity analysis. Informative priors on those sensitivity parameters can be elicited from subject-matter experts. We use Monte Carlo integration to compute the full data estimands. Performance of our approach is assessed using simulated datasets. Our methodology is motivated by, and applied to, data from a clinical trial on treatments for schizophrenia.
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影响因子：
2.7
作者：
Linero, A. R.
通讯作者：
Linero, A. R.
影响因子：
3.7
作者：
GEISSER, S;EDDY, WF
通讯作者：
EDDY, WF
DOI：
10.1093/biostatistics/1.4.465
发表时间：
2000-12-01
期刊：
Biostatistics (Oxford, England)
影响因子：
--
作者：
Henderson, R;Diggle, P;Dobson, A
通讯作者：
Dobson, A
影响因子：
1.9
作者：
Daniels MJ;Wang C;Marcus BH
通讯作者：
Marcus BH
影响因子：
3.7
作者：
Datta A;Banerjee S;Finley AO;Gelfand AE
通讯作者：
Gelfand AE