Gender Differences in the Colorado Stroke Registry
Gender Differences in the Colorado Stroke Registry
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DOI：
10.1161/strokeaha.108.541730
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发表时间：
2009-04-01
期刊：
影响因子：
8.3
通讯作者：
Wilde, Marsha
中科院分区：
文献类型：
--
作者：
Smith, Don B.;Murphy, Paul;Wilde, Marsha
背景和目的--中风的性别差异日益引起人们的关注。美国中风协会的患者管理工具Get With the Guiders-Stroke(GGS)被广泛用于提高中风护理中对质量指标的依从性，但它也提供了一个机会来分析急性中风设置中的性别差异。方法-我们使用了一个基于GGS的全州数据库来探索科罗拉多州中风的性别差异。我们分析了人口统计学、风险因素、生活方式、治疗方法和对治疗的反应。结果：在检查的126个数据元素中，有47个(37%)存在统计学上显著的性别差异。与男性相比，科罗拉多州的女性年龄更大，受急性中风的影响更大。危险因素分布在男女之间存在差异，男性的冠状动脉疾病、血脂异常、糖尿病、颈动脉狭窄和吸烟的发病率较高，而女性的房颤和高血压的发病率较高。血脂的治疗不那么积极，抗血栓药在女性中也不太常用。总体而言，女性急性卒中的治疗似乎比男性“不那么积极”。结论-GGS不仅可用于个别医院的质量改进计划。它还可以在州一级概述中风的临床方面，并可能阐明性别差异。(笔划。2009；40：1078-1081。)
Background and Purpose-Gender differences in stroke are matters of increasing interest. The American Stroke Association's patient management tool, Get with the Guidelines-Stroke (GGS) is widely used to increase adherence to quality indicators in stroke care, but it also provides an opportunity to analyze gender differences in the acute stroke setting.Methods-We used a state-wide database, based on GGS, to explore gender differences in stroke in Colorado. We analyze demographics, risk factors, lifestyles, treatments, and responses to treatment.Results-Of 126 data elements examined, statistically significant gender differences were noted for 47 (37%). As compared to men, women in Colorado were older and more significantly impacted by acute stroke. Risk factor profiles differed between the 2 genders, with men having a higher incidence of coronary artery disease, dyslipidemia, diabetes, carotid stenosis and tobacco smoking, while women had a higher incidence of atrial fibrillation and hypertension. Lipids were less aggressively treated and antithrombotics were less commonly used in women. Overall, acute stroke treatment of women appeared "less aggressive" than for men.Conclusions-GGS may be used not only for quality improvement initiatives in individual hospitals. It can also give an overview of clinical aspects of stroke at a state level, and may shed light on gender differences. (Stroke. 2009; 40:1078-1081.)