PREDICTIVE IMPLICATIONS OF VENTRICULAR PREMATURE CONTRACTIONS ASSOCIATED WITH TREADMILL STRESS TESTING
PREDICTIVE IMPLICATIONS OF VENTRICULAR PREMATURE CONTRACTIONS ASSOCIATED WITH TREADMILL STRESS TESTING
复制标题
DOI：
10.1161/01.cir.56.6.985
复制
发表时间：
1977-01-01
期刊：
影响因子：
37.8
通讯作者：
ELLESTAD, MH
中科院分区：
文献类型：
--
作者：
UDALL, JA;ELLESTAD, MH
对6500名接受负荷测试的患者收集了未来冠状动脉事件的随访数据；1327名患者出现了与一期或多期跑步机负荷测试(TST)相关的室性早搏(VPC)。在所有接受测试的患者中，有83%的人知道或怀疑患有心血管疾病。在随访5年中，1067例无VPC或缺血性ST段改变的患者发生新的冠状动脉事件(心肌梗死、心绞痛、心源性死亡)的年发生率为1.7%，758例单纯VPC组为6.4%，609例单纯缺血性ST段改变组为9.5%，569例VPC合并缺血性ST段改变组为11.4%。与TST相关的VPC的重要性很大程度上取决于受试者的临床状态。在接受TST检查以评估已知或可疑心血管疾病的患者中观察到的VPC，无论有无缺血性ST段异常，都是未来冠状动脉事件的明确危险因素。
Follow-up data on future coronary events was collected on 6500 patients who underwent stress testing; 1327 exhibited ventricular premature contractions (VPC) associated with 1 or more phases of treadmill stress testing (TST). Eighty-three percent of all pateents tested had known or suspected cardiovascular disease. The annual incidence of new coronary events (myocardial infarction, angina, cardiac death) during a 5 yr follow-up was 1.7% among 1067 patients without VPC or ischemic ST changes, 6.4% in 758 patients with VPC alone, 9.5% among 609 patients with ischemic ST changes alone and 11.4% in 569 patients with VPC plus ischemic ST changes. The significance of VPC associated with the TST rests largely upon the clinical status of the persons tested. VPC observed among patients referred for TST for the evaluation of known or suspected cardiovascular disease, with or without ischemic ST abnormailites, represent a definite risk factor for future coronary events.