Electrophysiology in Gullian‐Barré syndeome

Electrophysiology in Gullian‐Barré syndeome
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Gullian-Barré综合征的电生理学

DOI:
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发表时间:
1990
期刊:
影响因子:
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通讯作者:
D. Cornblath
D. Cornblath
中科院分区:
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文献类型:
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作者:
D. Cornblath

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临床电生理学研究对于评估格林-巴利综合征患者非常重要。几乎所有吉兰-巴利综合征患者都会出现脱髓鞘的生理证据,特别是在进行系列研究的情况下。提出了脱髓鞘的标准。关于患者结果的预后信息可以通过计算来自远端刺激的运动诱发复合肌肉动作电位幅度之和的平均值来推断。未来对吉兰-巴利综合征电生理学的研究应该允许更多地使用这些数据进行预测,并应该增强我们对该疾病机制的理解。
Clinical electrophysiological studies are important in the evaluation of patients with Guillain‐Barré syndrome. Physiological evidence of demyelination occurs in almost all patients with Guillain‐Barré syndrome, especially if serial studies are performed. Criteria for demyelination are proposed. Prognostic information concerning patient outcome can be deduced from computation of the mean of the summed motor evoked compound muscle action potential amplitudes from distal stimulation. Future studies of the electrophysiology of Guillain‐Barré syndrome should allow increased use of the data for prognostication and should enhance our understanding of the mechanisms of the disease.