RuH2(CO)(PPh3)3 catalyzed selective formation of 1,4-disubstituted triazoles from cycloaddition of alkynes and organic azides.
RuH2(CO)(PPh3)3 catalyzed selective formation of 1,4-disubstituted triazoles from cycloaddition of alkynes and organic azides.
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DOI：
10.1021/jo3008572
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发表时间：
2012-06
期刊：
影响因子：
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通讯作者：
P. Liu;Siyang Xiao Hai;Li Zhang;Sunny Kai San Tse;G. Jia
中科院分区：
文献类型：
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作者：
P. Liu;Siyang Xiao Hai;Li Zhang;Sunny Kai San Tse;G. Jia
研究发现，氢化钌配合物RuH(2)(CO)(PPh(3))(3)对末端炔烃和叠氮化物的环加成反应是有效的催化剂。在RuH(2)(CO)(PPh(3))(3)的存在下，不同的叠氮化物与一系列末端炔反应生成1，4-二取代的1，2，3-三唑，选择性为100%，产率中等至极高。
The ruthenium hydride complex RuH(2)(CO)(PPh(3))(3) was found to be an effective catalyst for the cycloaddition reactions of terminal alkynes and azides. In the presence of RuH(2)(CO)(PPh(3))(3), various azides reacted with a range of terminal alkynes to produce 1,4-disubstituted 1,2,3-triazoles with 100% selectivity and moderate to excellent yields.