Early childhood predictors of adult anxiety disorders

Early childhood predictors of adult anxiety disorders
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DOI:
10.1016/s0006-3223(99)00137-7
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发表时间:
1999-12-01
影响因子:
10.6
通讯作者:
Snidman, N
Snidman, N
中科院分区:
医学1区
文献类型:
--
作者:
Kagan, J;Snidman, N

文献摘要

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本文探讨了气质因素对儿童和青少年焦虑症状发展的影响。大约20%的健康儿童出生时就有气质偏差,这种偏向使他们在婴儿期对陌生的刺激有高度的反应,在幼年时对陌生的事件和人感到恐惧或回避。经历影响了这种最初的气质偏见,到了青春期,这一群体中约三分之一的人可能会表现出严重的社交焦虑迹象。这些儿童还可能有一个或多个生物学特征,包括交感神经更活跃的心血管系统,脑电中皮质激活的不对称性,有利于更活跃的右额叶,更高频率范围的脑电更大的功率,以及更窄的面部骨骼。三角洲暗示,这种气质偏差应该被概念化为限制形成始终如一的无畏和自发的个人特征的可能性,而不是决定焦虑或内向的表型。(C)1999年生物精神病学学会。
This paper considers the influence of temperamental factors on the development of anxious symptoms in children and adolescents.About 20 percent of healthy children are born with a temperamental bias that predisposes them to be highly reactive to unfamiliar stimulation as infants and to be fearful of or avoidant to unfamiliar events and people as young children. Experiences act on this initial temperamental bias and, by adolescence, about one-third of this group is likely to show signs of serious social anxiety. These children are also likely to have one or more biological features, including a sympathetically more reactive cardiovascular system, asymmetry of cortical activation in EEG favoring a more active right frontal area, more power in the EEG in the higher frequency range, and a narrower facial skeleton. The delta imply that this temperamental bias should be conceptualized as constraining the probability of developing a consistently fearless and spontaneous profile rather than as determining an anxious or introverted phenotype. (C) 1999 Society of Biological Psychiatry.