Pharmacogenetics of Psychotropic Drugs

Pharmacogenetics of Psychotropic Drugs
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精神药物的药物遗传学

DOI:
10.1017/cbo9780511543944
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发表时间:
2002
期刊:
--
影响因子:
--
通讯作者:
D. Nutt
D. Nutt
中科院分区:
--
文献类型:
--
作者:
S. A. Pandit;S. Argyropoulos;P. Kehoe;D. Nutt

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第一部分.引言:1.基因和精神药理学:探索界面伯纳德Lerer第二部分。临床背景和研究设计:2。从药物遗传学到精神药物反应的药物基因组学。马尔霍特拉3.神经精神药理学:基因与精神疾病分类学之间的接口托马斯。禁止4.精神药物遗传学中的方法论问题谢尔顿H.第五章.精神药物遗传学的统计方法第三部分。分子背景:6.精神药理学-神经发育界面在多巴胺能基因通路K。彼得·莱希,延斯·本宁霍夫和安吉丽卡施密特7. RNA加工调控与个体间变异。Niswender和琳达K.哈钦森第四部分药代动力学:8。精神药物代谢的遗传药理学。M.卡舒巴Basile和James L .肯尼迪9号。手性精神药物的遗传药理学研究。第五部分特定精神药物和疾病:10。氯氮平反应和神经递质受体靶点的遗传变异大卫A。Collier,Maria J. Arranz,Sarah Osborne,凯瑟凯瑟琳J. Aitchison,Janet Munro,Dalu Mancama and Robert W.第十一章.药物诱导的迟发性运动障碍的遗传因素。12.第十二章.功能基因连锁多态性区域在药物遗传学马可Catalano 13.情绪和焦虑障碍的替代表型和药物遗传学。肯尼迪14.抗焦虑药物和GABA-苯二氮卓受体复合物的药物遗传学Smita A。潘迪特、斯皮利奥斯V. Argyropoulous、帕特里克G. 15.第十五章.双相情感障碍的遗传因素和长期预防Martin Alda 16.抗惊厥药物反应性的遗传影响托马斯N.费拉罗17.载脂蛋白E作为阿尔茨海默病治疗中的标志物基思Schappert,皮埃尔Sevigny和Judes Poirier 18.遗传变异和药物依赖危险因素Joel Gelernter和亨利Kranzler第六部分。药物遗传学和脑成像:19。阿尔茨海默病和精神分裂症的脑成像和药物遗传学。詹姆斯·波特金Kennedy和P.第七部分:行业前景:20。精神药物发现与开发中的药物遗传学。波特、安凯瑟琳·范·货车·隆和拉里·阿尔斯蒂尔21。高通量单核苷酸多态性基因分型Anne Shalom和Ariel Darvasi指数。
Part I. Introduction: 1. Genes and psychopharmacology: exploring the interface Bernard Lerer Part II. Clinical Background and Research Design: 2. From pharmacogenetics to pharmacogenomics of psychotropic drug response Anil K. Malhotra 3. Neuropsychopharmacology: the interface between genes and psychiatric nosology Thomas A. Ban 4. Methodological issues in psychopharmacogenetics Sheldon H. Preskorn 5. Statistical approaches in psychopharmacogenetics Fabio Macciardi Part III. Molecular Background: 6. The psychopharmacogenetic-neurodevelopmental interface in serotonergic gene pathways K. Peter Lesch, Jens Benninghoff and Angelika Schmitt 7. RNA processing regulation and interindividual variation Colleen M. Niswender and Linda K. Hutchinson Part IV. Pharmacokinetics: 8. Pharmacogenetics of psychotropic drug metabolism Vural Ozdemir, Angela D. M. Kashuba, Vincenzo S. Basile and James L . Kennedy 9. Pharmacogenetics of chiral psychotropic drugs Pierre Baumann and Chin B. Eap Part V. Specific Psychotropic Drugs and Disorders: 10. Clozapine response and genetic variation in neurotransmitter receptor targets David A. Collier, Maria J. Arranz, Sarah Osborne, Katherine J. Aitchison, Janet Munro, Dalu Mancama and Robert W. Kerwin 11. Genetic factors underlying drug-induced tardive dyskinesia Ronnen H. Segman and Bernard Lerer 12. Functional gene-linked polymorphic regions in pharmacogenetics Marco Catalano 13. Alternative phenotypes and the pharmacogenetics of mood and anxiety disorders Emanuela Mundo and James L. Kennedy 14. Pharmacogenetics of anxiolytic drugs and the GABA-benzodiazepine receptor complex Smita A. Pandit, Spilios V. Argyropoulous, Patrick G. Kehoe and David J. Nutt 15. Genetic factors and long-term prophylaxis in bipolar disorder Martin Alda 16. Genetic influences on responsiveness to anticonvulsant drugs Thomas N. Ferraro 17. Apolipoprotein E as a marker in the treatment of Alzheimer's disease Keith Schappert, Pierre Sevigny and Judes Poirier 18. Genetic variation and drug dependence risk factors Joel Gelernter and Henry Kranzler Part VI. Pharmacogenetics and Brain Imaging: 19. Brain imaging and pharmacogenetics in Alzheimer's disease and schizophrenia Steven G. Potkin, James L. Kennedy and Vincenzo S. Basile Part VII. Industry perspectives: 20. Pharmacogenetics in psychotropic drug discovery and development William Z. Potter, AnnCatherine Van Lone and Larry Altstiel 21. High-throughput single nucleotide polymorphism genotyping Anne Shalom and Ariel Darvasi Index.