Limited Interaction Targeted Epidemiology of HIV in Sexual and Gender Minority American Adolescents and Adults: Feasibility of the Keeping it LITE Study.
Limited Interaction Targeted Epidemiology of HIV in Sexual and Gender Minority American Adolescents and Adults: Feasibility of the Keeping it LITE Study.
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DOI：
10.2196/30761
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发表时间：
2021-11-26
影响因子：
2.2
通讯作者：
Hosek S
中科院分区：
文献类型：
--
作者：
Gleason N;Serrano PA;Muñoz A;French A;Hosek S
在美国，尽管艾滋病毒公共卫生应对措施持续改善，但性少数男性和变性人，特别是青少年和年轻人的艾滋病毒感染率仍然居高不下。然而，在了解该社区在接受艾滋病毒护理和预防资源方面面临的障碍方面，仍然存在知识差距。为了解决这个问题，进行了keep it LITE研究，以评估艾滋病毒的危险因素和预防治疗的障碍，在一个大型的国家队列中，年轻的性少数男性和跨性别者是艾滋病毒感染的高危人群。本研究旨在评估招募大型远程队列的可行性，招募过程中遇到的挑战，以及为应对这些挑战所做的调整。招募了一个大型的全国性队列（n=3444），其中包括年轻的性少数男性和变性人。参与者是通过社交媒体上的广告招募的；针对女同性恋、男同性恋、双性恋、变性人和酷儿群体的社交应用；印刷广告;和口碑。在登记之前，参与者通过在家进行艾滋病毒检测或提供自己的检测文件来验证他们的艾滋病毒状况。生成描述性统计数据，并进行一系列逻辑回归，以评估招募方法、HIV检测方法和入学状况之间的人口统计学差异。keep it LITE研究在通过社交媒体招募参与者方面尤其成功，超过一半的参与者是通过Facebook、Instagram和Snapchat等社交媒体平台上的广告招募的。参与者也是通过口口相传的方式招募的；女同性恋、男同性恋、双性恋、变性人和酷儿应用（如Grindr、Scruff）；还有印刷广告，从这些来源招募的参与者往往年龄较大，风险较高。这项研究还成功地招募了大量跨性别青年，尤其是跨性别男性和非二元性别个体。尽管在实施艾滋病毒检测过程中遇到了一些障碍并克服了这些障碍，但家庭艾滋病毒检测是可以接受的，并且在年轻参与者中使用得更多。这项研究在招募13-17岁的参与者方面取得了有限的成功，因为入学率较低，而且在社交媒体平台上做广告存在障碍。本文还讨论了这些发现对未来性少数群体和跨性别青年艾滋病研究和干预方案发展的意义。在keep it LITE研究中使用的方法，特别是通过社交媒体招募，被发现是可行的，并且被参与者接受。
HIV infection rates among sexual minority men and transgender individuals, particularly adolescents and young adults, remain elevated in the United States despite continued improvement in the HIV public health response. However, there remains a knowledge gap in understanding the barriers faced by this community in receiving HIV care and prevention resources. To address this, the Keeping it LITE study was conducted to assess HIV risk factors and barriers to preventive treatment in a large national cohort of young sexual minority men and transgender individuals at high risk of HIV infection. This study aims to evaluate the feasibility of enrolling a large remote cohort, challenges encountered in recruitment, and adjustments made to address these challenges. A large national cohort (n=3444) of young sexual minority men and transgender individuals were recruited. Participants were recruited via advertisements on social media; social apps for lesbian, gay, bisexual, transgender, and queer individuals; print advertising; and word-of-mouth. Before enrolling, participants verified their HIV status using an at-home HIV test or by providing their own testing documentation. Descriptive statistics were generated, and a series of logistic regressions were conducted to evaluate demographic differences between recruitment methods, HIV testing methods, and enrollment status. The Keeping it LITE study was particularly successful in recruiting participants via social media, with over half of the participants recruited from advertisements on social media platforms such as Facebook, Instagram, and Snapchat. Participants were also recruited via word-of-mouth; lesbian, gay, bisexual, transgender, and queer apps (ie, Grindr, Scruff); and print advertisements, and participants recruited from these sources tended to be older and have a higher risk profile. The study was also successful in recruiting a large sample of transgender youth, particularly transgender men and nonbinary individuals. At-home HIV testing was acceptable and more heavily used by younger participants, although several barriers were encountered and overcome in the implementation of this testing. The study had more limited success in recruiting participants aged 13-17 years because of lower enrollment rates and barriers to advertising on social media platforms. The implications of these findings for the future development of HIV research and intervention protocols among sexual minorities and trans youth are discussed. The methods used in the Keeping it LITE study, particularly recruitment via social media, were found to be feasible and acceptable to participants.