Hantavirus and arenavirus antibodies in persons with occupational rodent exposure.
Hantavirus and arenavirus antibodies in persons with occupational rodent exposure.
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DOI：
10.3201/eid1304.061509
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发表时间：
2007-04
影响因子：
11.8
通讯作者：
Ksiazek TG
中科院分区：
文献类型：
--
作者：
Fulhorst CF;Milazzo ML;Armstrong LR;Childs JE;Rollin PE;Khabbaz R;Peters CJ;Ksiazek TG
在工作中处理新托明或西格莫顿汀啮齿动物的人感染的风险较低。啮齿动物是 Sin Nombre 病毒、已知在北美引起汉坦病毒肺综合征的其他 4 种汉坦病毒和 3 种北美沙粒病毒的主要宿主。对来自 757 名曾在北美从事过啮齿类动物工作并处理过新托明或西格莫顿啮齿类动物的人员的血清样本进行了检测，以检测抗辛诺布尔病毒、白水阿罗约病毒、瓜纳里托病毒和淋巴细胞性脉络膜脑膜炎病毒的抗体。 4 人中发现了针对 Sin Nombre 病毒的抗体，2 人中发现了针对白水阿罗约病毒或瓜纳里托病毒的抗体，没有人发现了针对淋巴细胞脉络膜脑膜炎病毒的抗体。这些结果表明，在北美，从事与新托明或西格莫顿啮齿动物密切身体接触的职业的人感染汉坦病毒或沙粒病毒的风险通常较低。
Risk for infection was low among those who handled neotomine or sigmodontine rodents on the job. Rodents are the principal hosts of Sin Nombre virus, 4 other hantaviruses known to cause hantavirus pulmonary syndrome in North America, and the 3 North American arenaviruses. Serum samples from 757 persons who had worked with rodents in North America and handled neotomine or sigmodontine rodents were tested for antibodies against Sin Nombre virus, Whitewater Arroyo virus, Guanarito virus, and lymphocytic choriomeningitis virus. Antibodies against Sin Nombre virus were found in 4 persons, against Whitewater Arroyo virus or Guanarito virus in 2 persons, and against lymphocytic choriomeningitis virus in none. These results suggest that risk for infection with hantaviruses or arenaviruses usually is low in persons whose occupations entail close physical contact with neotomine or sigmodontine rodents in North America.