Regioselective synthesis of the bridged tricyclic core of Garcinia natural products via intramolecular aryl acrylate cycloadditions.
Regioselective synthesis of the bridged tricyclic core of Garcinia natural products via intramolecular aryl acrylate cycloadditions.
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DOI：
10.1021/ol017278w
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发表时间：
2002-02
期刊：
影响因子：
5.2
通讯作者：
Eric J. Tisdale;C. Chowdhury;B. Vong;Hongmei Li;E. Theodorakis
中科院分区：
文献类型：
--
作者：
Eric J. Tisdale;C. Chowdhury;B. Vong;Hongmei Li;E. Theodorakis
[reaction: see text] Two different routes to the tricyclic core of Garcinia-derived natural products are described. The first approach is based on a tandem Claisen/Diels-Alder rearrangement and delivers the desired lactone 14. The second approach, employing a Wessely oxidation/Diels-Alder protocol, leads to the same caged heterocycle, albeit with modified constitution.
