The clinics ofHHV-6 infection inCOVID-19 pandemic: Pityriasis rosea and Kawasaki disease

The clinics ofHHV-6 infection inCOVID-19 pandemic: Pityriasis rosea and Kawasaki disease
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DOI:
10.1111/dth.13730
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发表时间:
2020-06-29
影响因子:
3.6
通讯作者:
Temiz, Selami Aykut
Temiz, Selami Aykut
中科院分区:
医学4区
文献类型:
--
作者:
Dursun, Recep;Temiz, Selami Aykut

文献摘要

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2019年底,在中国武汉首次发现了一种新型冠状病毒家族(SARS-CoV-2),它可以在人类和动物中发现,具有多种品种和临床症状,名称为新型冠状病毒病2019 (COVID-19)。在文献中,通常强调与疾病相关的皮肤症状。然而,目前尚不清楚这种进入我们生活的新型SARS-CoV-2病毒是否在皮肤病的发病机制中发挥作用。通过检索医院自动化系统和患者档案,对2019年4月1日至5月15日和2020年4月1日至5月15日皮肤科门诊收治的患者进行回顾性分析。将相同月份纳入研究的原因是为了排除季节对疾病的影响。大流行后,到皮肤科门诊就诊的玫瑰糠疹和川崎病患者明显增多。我们的研究是第一个显示玫瑰糠疹在大流行期间增加的研究。我们认为这种增加与HHV-6再激活有关。在此,我们希望引起人们对两种疾病的关注,其中人类疱疹6 (HHV-6)被指控为病因:川崎病和玫瑰糠疹。
A new type of coronavirus family (SARS-CoV-2), which can be found in humans and animals, with many varieties and clinical symptoms, was first seen in Wuhan, China in late 2019, under the name novel Coronavirus Disease 2019 (COVID-19). In the literature, cutaneous symptoms related to the disease are generally emphasized. However, it is not yet known whether this new SARS-CoV-2 virus, which has entered our lives, plays a role in the etiopathogenesis of dermatological diseases. The patients who were admitted to the dermatology outpatient clinic between 1 April and 15 May 2019, and on 1 April and 15 May 2020 were retrospectively analyzed by searching the hospital automation system and patient files. The reason for the same months to be included in the study was to exclude seasonal effects on the diseases. After pandemic, the number of patients with Pityriasis rosea and Kawasaki disease increased significantly in patients who applied to the dermatology outpatient clinic. Our study is the first study showing Pityriasis rosea increase during the pandemic period. We think that this increase is related to HHV-6 reactivation. Herein, we wanted to draw attention to two diseases in which Human Herpes 6 (HHV-6) was accused in etiopathogenesis: Kawasaki disease and Pityriasis rosea.