Prevalence of Radiographic Cochlear-Facial Nerve Dehiscence
Prevalence of Radiographic Cochlear-Facial Nerve Dehiscence
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DOI：
10.1097/mao.0000000000002015
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发表时间：
2018-12-01
影响因子：
2.1
通讯作者：
Blevins, Nikolas H.
中科院分区：
文献类型：
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作者：
Song, Yohan;Alyono, Jennifer C.;Blevins, Nikolas H.
目的：确定影像学检查耳蜗-面神经裂开（CFD）的患病率。研究设计：回顾性放射学研究。设置：两个三级转诊中心。患者：206例颞骨计算机断层扫描（CT）扫描2014年至2017年间，来自两个学术机构的耳科/神经耳科患者（共405耳）。干预：诊断。主要结果指标：在冠状面CT上测量耳蜗-面神经间隔宽度（CFPW），定义为耳蜗基底回与面神经（FN）间的最短距离。我们使用逻辑回归分析，以确定积极的预测因素的放射学证据的CFD.Results：放射学CFD的总患病率为5.4%（22/406耳）。9.2%的患者（19/206）患有CFD。在这19名患者中，只有1名患者有混合性听力损失，无法用任何其他前庭或听觉病因解释。206例患者中有3例（1.4%）双耳裂开。平均CFPW为0.6 ± 0.2 mm，输卵管宽度为1.1 ± 0.02 mm（n = 405）。年龄较大，使用传统的CT扫描，和较薄的CT切片厚度是显着的预测因素为放射学CFD.Conclusions：CFD的放射学患病率高于组织学研究报告，并可能高估了真正的流行CFD。临床医生在考虑将其作为第三窗口症状的潜在原因时应记住这一点。
Objective: To determine the prevalence of radiographic cochlear-facial nerve dehiscence (CFD).Study Design: Retrospective radiological study.Setting: Two tertiary-referral centers.Patients: Two hundred six temporal-bone computed tomography (CT) scans (405 total ears) of otology/neurotology patients from two academic institutions between the years 2014 and 2017.Intervention: Diagnostic.Main Outcome Measures: The cochlear-facial nerve partition width (CFPW) was measured on coronal CT sections and defined as the shortest distance between the cochlear basal turn and facial nerve (FN) labyrinthine segment. We used logistics regression analyses to determine positive predictors for radiographic evidence of CFD.Results: The overall prevalence of radiographic CFD was 5.4% (22/406 ears). 9.2% of patients (19/206) had CFD. Of these 19 patients, only one patient had mixed hearing loss that could not be explained by any other vestibular or auditory etiology. Three out of 206 patients had dehiscence in both ears (1.4%). The average CFPW was 0.6 +/- 0.2 mm, and fallopian canal width was 1.1 +/- 0.02 mm (n = 405). Older age, use of traditional CT scans, and thinner CT slice thickness were significant predictors for radiographic CFD.Conclusions: The radiographic prevalence of CFD is higher than what is reported in histologic studies, and may overestimate the true prevalence of CFD. The clinician should keep this in mind when considering this as potential cause for third-window symptoms.