Virulence of Streptococcus mutans: immunochemical characterization of a serotype g-defective mutant (C307)

Virulence of Streptococcus mutans: immunochemical characterization of a serotype g-defective mutant (C307)
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变形链球菌的毒力:血清型 g 缺陷突变体 (C307) 的免疫化学特征

DOI:
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发表时间:
1980
影响因子:
3.1
通讯作者:
J. Mcghee
J. Mcghee
中科院分区:
医学2区
文献类型:
--
作者:
M. Hirasawa;H. Kiyono;T. Shiota;S. Michalek;J. Mcghee

文献摘要

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变异链球菌6715野生型的突变体C307已被证明具有少量的兰斯菲尔德或Rantz-Randall可提取的血清型抗原。定量分析采用联合免疫吸附和放射免疫扩散的抗S。变形链球菌G型特异性血清表明,C307表现出低于S. mutans 6715野生型。
A mutant of Streptococcus mutans 6715 wild type designated C307 has been shown to possess a small amount of either Lancefield- or Rantz-Randall-extractable serotype antigen. Quantitative analysis employing combined immunoabsorption and radial immunodiffusion of anti-S. mutans serotype-specific serum demonstrated that C307 exhibited less than 1% of the amount of serotype g antigen normally expressed in S. mutans 6715 wild type.