Determination of major bioactive compounds from olive leaf
Determination of major bioactive compounds from olive leaf
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DOI：
10.1016/j.lwt.2015.05.001
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发表时间：
2015-11-01
影响因子：
6
通讯作者：
Rada, Mirela
中科院分区：
文献类型：
--
作者：
Guinda, Angeles;Maria Castellano, Jose;Rada, Mirela
橄榄叶是修剪橄榄树产生的农业残留物，可被视为可用的工业副产品。橄榄树的生物化学特征是存在开环环烯醚萜、碳水化合物、糖醇和萜类化合物。橄榄苦苷，特别是丰富的橄榄叶（高达14% DW），具有最大的生物学意义。多元醇甘露醇，代表约。占叶干重的3%，由于其甜度高且热量低，已被食品和制药工业用作赋形剂。同样，橄榄叶中的油酸浓度很高（约为3% DW），并且具有非常重要的药理学特性。在这项工作中，我们描述了一种新的程序，用于测定的主要生物活性化合物从橄榄叶固相萃取和高效液相色谱。这些生物活性化合物中确定的四个最重要的西班牙油橄榄品种。橄榄叶含有大量的油酸、橄榄苦苷和甘露醇，其回收可能对制药、化妆品和食品工业有意义。在这项工作中提出的分析方法将作为一个非常合适的工具，用于控制任何工业过程，以获得这些高附加值的化合物。(C)2015爱思唯尔有限公司版权所有。
Olive leaves are an agricultural residue resulting from the pruning of olive trees that may be considered an available industrial byproduct. The olive tree is biochemically characterized for the presence of secoiridoids, carbohydrates, sugar alcohols, and terpenoids. Oleuropein, especially abundant in the olive leaves (up to 14% DW), have the greatest biological interest. The polyalcohol mannitol, which represents approx. a 3% of the leaf dry weight, has been used by the food and pharmaceutical industries as excipient, due to its high sweetness and poor caloric power. Likewise, oleanolic acid is present in the olive leaf in significant concentrations (approximate to 3% DW) and has been endorsed with very important pharmacological properties. In this work we describe a novel procedure for the determination of the major bioactive compounds from the olive leaf by SPE and HPLC. These bioactive compounds were determined in the four most significant Spanish Olea europaea cultivars. Olive leaf contains important amounts of oleanolic acid, oleuropein and mannitol, whose recovery could be interesting for the pharmaceutical, cosmetics and food industries. The analytical methodology presented in this work would serve as a very suitable tool for the control of any industrial process designed to obtain these high added-value compounds. (C) 2015 Elsevier Ltd. All rights reserved.