INFLUENCE OF TIME OF MATING AND PACED COPULATION ON INDUCTION OF PSEUDOPREGNANCY IN CYCLIC FEMALE RATS
INFLUENCE OF TIME OF MATING AND PACED COPULATION ON INDUCTION OF PSEUDOPREGNANCY IN CYCLIC FEMALE RATS
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DOI：
10.1530/jrf.0.0900375
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发表时间：
1990-11-01
期刊：
影响因子：
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通讯作者：
ERSKINE, MS
中科院分区：
文献类型：
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作者：
FRYE, CA;ERSKINE, MS
本实验旨在研究在行为发情过程中，雌性对交配刺激的敏感性和性行为模式是否会发生变化，这些变化可能会影响黄体维持的可能性。循环雌性大鼠在发情前晚上（21:00 h）或发情清晨（05:00 h）交配，在允许或不允许起搏或与雄性接触的条件下接受5或10次雄性的引入。在交配过程中，测量了雌性的性接受程度、雄性交配的时间和踱步行为。通过在交配后14天检查阴道涂片和在实验结束时检查子宫是否存在胎儿来确定每只动物是否发生假妊娠或妊娠。在两个交配时间，与雄性交配的节奏增加了黄体活动延长的可能性。然而，与前一天晚上21:00相比，在05:00进行无节奏交配后，雌性更有可能成为假怀孕。在那些在交配过程中射精的雌性中，各组之间的怀孕率没有差异。发情期对宫颈阴道刺激敏感性的改变与性接受性或节奏行为的改变无关。因此，在发情期结束时，宫颈阴道刺激诱导假妊娠的能力会增加，但在此期间，调节接受这种刺激的行为机制保持不变。
The present experiment was designed to examine whether changes occur during the course of behavioural oestrus in the sensitivity of the female to copulatory stimulation and in patterns of sexual behaviour which might influence the likelihood of luteal maintenance. Cyclic female rats were mated on the evening of pro-oestrus (21:00 h) or early on the morning of oestrus (05:00 h) and received either 5 or 10 intromissions from males under conditions which allowed or did not allow pacing or contacts with males to occur. During mating, the levels of sexual receptivity, the timing of sexual mounts from males, and pacing behaviours were measured. The occurrence of pseudopregnancy or pregnancy in each animal was determined by examining vaginal smears for 14 days after mating and by examining the uterus for the presence of fetuses at the end of the experiment. At both mating times, pacing of copulation with males increased the likelihood of prolonged luteal activity. However, females were more likely to become pseudopregnant following non-paced mating at 05:00 h than at 21:00 the previous evening. Of those females receiving an ejaculation during mating, no differences were seen between groups in the incidence of pregnancy. This change in sensitivity to cervical-vaginal stimulation during oestrus was not associated with changes in sexual receptivity or pacing behaivour. The ability of cervical-vaginal stimulation to induce pseudopregnancy therefore increases towards the end of the period of oestrus, but the behavioural mechanisms which regulate receipt of such stimulation remain constant during that time.