Prostate cancer screening: the problem of overdiagnosis and lessons to be learned from breast cancer screening
Prostate cancer screening: the problem of overdiagnosis and lessons to be learned from breast cancer screening
复制标题
DOI：
10.1016/s0959-8049(00)00119-2
复制
发表时间：
2000-07-01
影响因子：
8.4
通讯作者：
Gervasi, G
中科院分区：
文献类型：
--
作者：
Ciatto, S;Zappa, M;Gervasi, G
前列腺癌筛查是一个相对较新的程序，仍在前瞻性随机试验中进行实验评估。前瞻性研究的设计主要是基于其他癌症筛查的经验，特别是乳腺癌，这方面有几项对照研究的数据。不幸的是，乳腺癌与前列腺癌非常不同，特别是在早期诊断等方面，因此，最初基于乳腺癌筛查所传授的教训而建立的筛查过程需要根据目前正在进行的筛查经验产生的数据进行不断的重新评估和调整。在本文中，我们将考虑前列腺癌筛查最具争议的方面，并将前列腺筛查与乳腺癌筛查进行比较，以促进对当前问题和教训的更好理解。(C)2000爱思唯尔科技有限公司版权所有。
Screening for prostate cancer is a relatively new procedure, still under experimental evaluation within prospective randomised trials. The design of prospective studies has been mainly based on the experience of other cancer screenings, particularly breast cancer, for which data of several controlled studies are available. Unfortunately, breast cancer is very different from prostate cancer, particularly for aspects such as early diagnosis and, thus the screening process, originally modelled on the basis of the lesson taught by breast cancer screening, needs continuous re-evaluation and adjustment, based on data which are now being produced from ongoing screening experiences. In this paper, we will consider the most controversial aspects of prostate cancer screening and compare prostate screening with breast cancer screening in order to promote a better understanding of the current problems and lessons to be learned. (C) 2000 Elsevier Science Ltd. All rights reserved.