Olfactory hallucinations in Alzheimer's disease
Olfactory hallucinations in Alzheimer's disease
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DOI：
10.1017/neu.2020.33
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发表时间：
2021-02-01
影响因子：
3.8
通讯作者：
Laroi, Frank
中科院分区：
文献类型：
--
作者：
El Haj, Mohamad;Laroi, Frank
我们评估了阿尔茨海默病 (AD) 患者出现幻嗅的频率、持续时间和不愉快程度。邀请 31 名 AD 患者的受访者对幻嗅、幻听、幻视的频率、持续时间和不愉快程度进行评分。分析表明，与幻听或幻视相比，幻嗅的发生率较低。结果还表明，幻嗅的持续时间从几秒到一分钟不等，其持续时间与幻听和幻视的持续时间相似。与幻听或幻视相比，幻嗅被评为令人不快。最后，幻嗅与抑郁症显着相关。我们的研究结果表明，幻嗅很少发生，但当幻嗅发生时，AD 患者会感到相对不愉快。我们的研究结果还证明了 AD 中的幻嗅与精神特征（即抑郁症）之间的关系。
We assessed the frequency, duration, and degree of unpleasantness of olfactory hallucinations in Alzheimer's disease (AD). Informants of 31 AD patients were invited to rate the frequency, duration, and degree of unpleasantness of olfactory, auditory, and visual hallucinations. Analysis demonstrated little occurrence of olfactory hallucinations compared with auditory or visual hallucinations. Results also demonstrated that olfactory hallucinations span from a few seconds to one minute, a duration that was similar to that of auditory and visual hallucinations. Olfactory hallucinations were rated as unpleasant compared with auditory or visual hallucinations. Finally, olfactory hallucinations were significantly correlated with depression. Our findings demonstrate little occurrence of olfactory hallucinations but that when they occur, they are experienced as relatively unpleasant in AD patients. Our findings also demonstrate a relationship between olfactory hallucinations and psychiatric characteristics (i.e., depression) in AD.