ANALYSIS OF THE ELECTRO-OCULOGRAMS OF A SERIES OF NORMAL SUBJECTS*
ANALYSIS OF THE ELECTRO-OCULOGRAMS OF A SERIES OF NORMAL SUBJECTS*
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一系列正常受试者的眼电图分析*
DOI：
10.1136/bjo.46.8.468
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发表时间：
1962
影响因子：
4.1
通讯作者：
Adel Barrada
中科院分区：
文献类型：
--
作者：
G. Arden;Adel Barrada
在之前的论文中，已经描述了如何将眼动电位用作视网膜功能的临床测试（*眼电图，EOG）。对拟议的临床试验进行了详细的理论和实践说明（Arden、Barrada 和 Kelsey，1962），并对之前的工作进行了回顾。在本文中，我们将分析对正常眼睛的测试结果，尽管已经简要提及了一些结果。下面描述的结果是在 15 个月的时间内获得的，在此期间，日常工作由多个人承担，并且临床测试的确切程序也不断发展。因此，通过对结果的分析，可以发现技术的修改（包括故意的变化，以及由于实验者的个体特性而引起的变化）如何影响测试中获得的值。这样的分析不仅使人们能够确定患病眼睛的检查结果是否与正常眼睛有显着差异，而且还有助于指导其他工作人员制定类似的测试。此外，正常受试者还包括一系列单眼无晶状体眼。从眼电图（视网膜功能测试）的角度来看，这些眼睛可能被认为是正常的，但他们的研究允许进一步分析晶状体对人眼站立电位的可能贡献。方法 (a) 受试者。-分析涉及 91 只眼睛获得的结果，这些结果被分为两组：在我们眼科研究所的同事身上进行了 39 项初步实验，并在该研究所的特殊诊所抽取的患者中获得了 52 项结果。除了 14 名单眼无晶体眼患者外，所有受试者的视力均正常，视野完整，无心血管疾病，并且在大多数情况下没有任何涉及眼睛的疾病史。这些患者均无近视史，矫正后视力正常，视野饱满，仅眼前节外伤后摘除晶状体，手术成功且简单。六例被诊断患有功能性神经障碍（癔症、行为缺陷），两例患有中枢性病变。
IN previous papers, a description has been given of the way in which the eye movement potential can be used as a clinical test of retinal function (the *electro-oculogram, EOG). A detailed theoretical and practical account of the proposed clinical test has been given (Arden, Barrada, and Kelsey, 1962) and previous work has been reviewed. In this paper the results of tests upon normal eyes will be analysed, though some of the findings have already been briefly mentioned. The results described below were obtained over a period of 15 months, during which time the routine work was undertaken by more than one person, and the exact procedure of the clinical test was evolved. By analysis of the res'Llts it is therefore possible to discover how modifications of technique (both deliberate variations, and those due to the individual peculiarities of the experimenter) can affect the values obtained in the test. Such an analysis not only enables one to decide whether the findings in diseased eyes depart significantly from the normal, but will also help to guide other workers in the elaboration of similar tests. In addition, the normal subjects have included a series of uniocular aphakics. From the point of view of the EOG, which is a test of retinal function, these eyes may be considered normal, but their investigation has permitted further analysis of the possible contribution of the lens to the standing potential of the human eye. Methods (a) Subjects.-The analysis is concerned with the results obtained on 91 eyes, which have been divided into two groups: 39 preliminary experiments were performed upon our colleagues at the Institute of Ophthalmology, and 52 results were obtained in patients drawn from the special clinics of the Institute. All the subjects had normal visual acuity, full fields, no cardiovascular disease, and in most cases no history of any disease involving the eye, apart from fourteen patients with uniocular aphakia. In these there was no history of myopia, vision was normal after correction, and the fields were full, the lens having been removed after trauma involving the anterior segment only, the operation having been successful and uncomplicated. Six cases were diagnosed as suffering from functional nervous disorders (hysteria, behavioural defects) and two from central lesions.