Salivary Glands, Saliva and Oral Findings in COVID-19 Infection
Salivary Glands, Saliva and Oral Findings in COVID-19 Infection
复制标题
DOI：
10.1590/pboci.2020.112
复制
发表时间：
2020-01-01
期刊：
影响因子：
--
通讯作者：
Nogueira, Fernando Neves
中科院分区：
文献类型：
--
作者：
Pedrosa, Marlus da Silva;Sipert, Carla Renata;Nogueira, Fernando Neves
全球正面临由严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）引起的新型冠状病毒病2019 （COVID-19）的威胁。尽管为遏制疾病传播作出了若干努力，但它仍然构成国际关注的突发公共卫生事件。科学文献中发表的几份报告呼吁人们注意口腔作为潜在感染途径、对牙科实践的影响以及在COVID-19诊断中使用唾液。本文的目的是概述在SARS-CoV-2感染背景下唾液腺和唾液的文献。简要讨论了COVID-19患者的味觉障碍和口腔检查结果。文献表明，SARS-CoV-2可以感染唾液腺。但是，不能推测它们是新冠病毒的宿主。此外，COVID-19患者还出现了一些口腔反应，包括唾液分泌不足和味觉障碍。少数报告显示，口腔溃疡和水疱与SARS-CoV-2感染有关。然而，它仍然没有被完全理解，并可能导致错误的假设。总的来说，需要进一步的研究来了解唾液腺和唾液在SARS-CoV-2感染背景下的真正作用。
The world is under the threat of the novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite several efforts to contain the disease spread, it still constitutes a public health emergency of international concern. Several published reports in the scientific literature called attention of the oral cavity as the potential route of infection, the implications for dental practice and the use of saliva in the diagnose of the COVID-19. The aim of this article is to provide an overview of the literature on the salivary glands and saliva in the context of SARS-CoV-2 infection. A brief discussion of taste disturbances and oral findings in COVID-19 patients is also presented. The literature shows that SARS-CoV-2 could infect the salivary glands. It is not possible, however, to make speculations regarding them as reservoirs for the SARS-CoV-2. In addition, patients with COVID-19 presented several oral repercussions, including hyposalivation and taste disturbances. A few reports showed oral ulcers and blisters associated with SARS-CoV-2 infection. However, it remains not fully understood and might lead to erroneous assumptions. Overall, further studies are necessary to understand the real role of salivary glands and saliva in the context of SARS-CoV-2 infection.