Dataset on the synthesis and physicochemical characterization of blank and curcumin encapsulated sericin nanoparticles obtained from Philosamia ricini silkworm cocoons
Dataset on the synthesis and physicochemical characterization of blank and curcumin encapsulated sericin nanoparticles obtained from Philosamia ricini silkworm cocoons
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DOI：
10.1016/j.dib.2019.104359
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发表时间：
2019-10-01
期刊：
影响因子：
1.2
通讯作者：
Das, Ratul Kumar
中科院分区：
文献类型：
--
作者：
Bhuyan, Devangana;Greene, George Warren;Das, Ratul Kumar
该数据集呈现了从蓖麻蚕（Philosamia ricini）（也称为Ahimsa丝或Peace丝或Eri）获得的空白和姜黄素包封的丝胶蛋白纳米颗粒的合成和物理化学表征。蓖麻蚕丝胶蛋白的应用报道极少。采用高温高压法从蚕茧中提取丝胶。以丙酮为脱溶剂，采用脱溶剂法制备了纳米丝胶蛋白。以姜黄素为疏水模型药物，将其包封于纳米粒中。通过不同的仪器分析对空白和姜黄素包封的丝胶蛋白纳米粒进行了理化表征。纳米粒子的大小和表面电荷随所用浓度的变化而变化。包封率和包封量随姜黄素浓度的变化而变化。这些结果表明蓖麻蚕茧中的丝胶蛋白具有应用潜力。(C)2019作者爱思唯尔公司出版
The dataset presents the synthesis and physicochemical characterization of blank and curcumin encapsulated sericin protein nanoparticles obtained from Philosamia ricini (also known as Ahimsa silk or Peace silk or Eri). Reports on application of sericin protein obtained from P. ricini are scanty at best. Sericin was extracted from the cocoons by high temperature and high pressure method. Synthesis of sericin nanoparticles was carried out by desolvation method using acetone as the desolvating agent. Curcumin was used as a hydrophobic model drug and was encapsulated into the sericin nanoparticles. Physicochemical characterization of the blank and curcumin encapsulated sericin nanoparticles were carried out by different instrumental analyses. The size and surface charges of sericin nanoparticles changed with the variation of applied sericin concentration. Encapsulation efficiency and loading capacity of the encapsulated sericin nanoparticles showed variation with curcumin concentration. The obtained data indicated the applicative potentials of sericin protein extracted from Philosamia ricini silkworm cocoons. (C) 2019 The Authors. Published by Elsevier Inc.