[Persorption of microparticles].
[Persorption of microparticles].
复制标题
[微粒的吸附]。
DOI：
--
复制
发表时间：
1993
期刊：
影响因子：
--
通讯作者：
G. Volkheimer
中科院分区：
文献类型：
--
作者：
G. Volkheimer
直径在微米范围内的固体硬微粒，如淀粉颗粒、花粉、纤维素颗粒、纤维和晶体，有规律地从消化道中大量摄入。运动因子在上皮细胞层的细胞旁渗透中发挥重要作用。微粒从上皮下区域通过淋巴和血管被运走。可以使用简单的方法在体液中检测到它们：口服给药后仅几分钟，它们就可以在外周血流中找到。我们观察到它们进入尿液、胆汁、脑脊液、肺泡腔、腹膜腔、母乳，并经胎盘进入胎儿血流。由于吸附的微粒可以栓塞小血管，这涉及微血管学问题，特别是在中枢神经系统区域。由潜在过敏原或污染物组成或作为污染物载体的栓塞微粒的长期沉积具有免疫学和环境技术重要性。许多现成食品含有大量能够吸收的微粒。
Solid, hard microparticles, such as starch granules, pollen, cellulose particles, fibres and crystals, whose diameters are well into the micrometre range, are incorporated regularly and in considerable numbers from the digestive tract. Motor factors play an important part in the paracellular penetration of the epithelial cell layer. From the subepithelial region the microparticles are transported away via lymph and blood vessels. They can be detected in body fluids using simple methods: only a few minutes after oral administration they can be found in the peripheral blood-stream. We observed their passage into urine, bile, cerebrospinal fluid, the alveolar lumen, the peritoneal cavity, breast milk, and transplacentally into the fetal blood-stream. Since persorbed microparticles can embolise small vessels, this touches on microangiological problems, especially in the region of the CNS. The long-term deposit of embolising microparticles which consist of potential allergens or contaminants, or which are carriers of contaminants, is of immunological and environmental-technical importance. Numerous ready-made foodstuffs contain large quantities of microparticles capable of persorption.