The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation
The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation
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DOI：
10.1039/b305798b
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发表时间：
2003-01-01
影响因子：
4.9
通讯作者：
Jericho, KL
中科院分区：
文献类型：
--
作者：
Gooding, JJ;Chou, A;Jericho, KL
基于单链 DNA 和双链体之间的灵活性变化，提出了一种检测 DNA 杂交的无标记电化学方法，该变化引起离子门控效应，其中杂交打开电极以进入离子。
A label free electrochemical method of detecting DNA hybridisation is presented based on the change in flexibility between a single strand of DNA and a duplex causing an ion-gating effect where hybridisation opens up the electrode to access of ions.