Does orbital proprioception contribute to gaze stability during translation?
Does orbital proprioception contribute to gaze stability during translation?
复制标题
眼眶本体感觉是否有助于平移过程中的注视稳定性？
DOI：
10.1007/s00221-011-2873-y
复制
发表时间：
2011
影响因子：
2
通讯作者：
Newlands,ShawnD
中科院分区：
文献类型：
--
作者：
Wei,Min;Lin,Nan;Newlands,ShawnD
平移运动引起视网膜图像滑移，随物体距离的变化而变化。大脑必须实时了解双眼的位置，以便调整眼球运动，以减少视网膜滑动。眼位信息的两个潜在来源是眼眶本体感觉和眼位的内部表征源自中央眼运动信号。为了研究眶本体感觉信息的作用，在左展神经微刺激下，两只恒河猴沿耳间轴向左或向右平移运动时，左眼的位置受到干扰。微刺激使眼睛侧向旋转，激活眼肌本体感受器，同时保持中央运动指令不受干扰。我们发现微刺激引起的眼位变化不影响外展（外直肌）方向的平移VOR，但它确实影响内收（内直肌）方向的反应。我们的研究结果表明，至少在同侧头部运动期间，本体感觉输入似乎参与了TVOR反应，并且本体感觉对TVOR的影响可能涉及到向动眼核发送的收敛相关信号。然而，来自中央眼运动信号的眼位置的内部表征可能在提供眼位置信息方面起着主要作用，用于在平移运动中缩放眼运动，特别是在外展方向上。
Translational motion induces retinal image slip which varies with object distance. The brain must know binocular eye position in real time in order to scale eye movements so as to minimize retinal slip. Two potential sources of eye position information are orbital proprioception and an internal representation of eye position derived from central ocular motor signals. To examine the role of orbital proprioceptive information, the position of the left eye was perturbed by microstimulation of the left abducens nerve during translational motion to the right or left along the interaural axis in two rhesus macaques. Microstimulation rotated the eye laterally, activating eye muscle proprioceptors, while keeping central motor commands undisturbed. We found that microstimulation-induced eye position changes did not affect the translational VOR in the abductive (lateral rectus) direction, but it did influence the responses in the adductive (medial rectus) direction. Our findings demonstrate that proprioceptive inputs appear to be involved in the TVOR responses at least during ipsilateral head movements and proprioceptive influences on the TVOR may involve vergence-related signals to the oculomotor nucleus. However, internal representation of eye position, derived from central ocular motor signals, likely plays the dominant role in providing eye position information for scaling eye movements during translational motion, particularly in the abducent direction.