Pattern formation in Dictyostelium discoideum: an analysis of mutants altered in cell proportioning.
Pattern formation in Dictyostelium discoideum: an analysis of mutants altered in cell proportioning.
复制标题
盘基网柄菌的模式形成：对细胞比例改变的突变体的分析。
DOI：
10.1016/s0012-1606(81)80002-4
复制
发表时间：
1981
影响因子：
2.7
通讯作者：
Loomis,WF
中科院分区：
文献类型：
--
作者：
Morrissey,JH;Farnsworth,PA;Loomis,WF
先前对盘基网骨藻的研究表明，在迁移的蛞蝓前1/5的细胞在生化和超微结构上与后细胞不同。这种分化模式与两种细胞类型未来命运的差异有关，这导致了这样的结论，即孢子和茎分化所必需的准备工作开始于蛞蝓阶段。我们报告的突变体的分析，其中孢子和柄细胞的比例急剧改变，但在蛞蝓的几个分化的模式基本上是野生型。根据这些结果讨论了与D. discoideum的图案形成和形态发生有关的模型。
Previous studies ofDictyostelium discoideumhave demonstrated that the cells in the anterior fifth of the migrating slug differ biochemically and ultrastructurally from the posterior cells. This pattern of differentiation has been correlated with the difference in prospective fate of the two clel types, which has led to the conclusion that preparations essential for spore and stalk differentiation begin during the slug stage. We report the analysis of mutants in which the proportions of spore and stalk cells is drastically altered and yet in which the pattern of several differentiations in slugs is essentially wild type. Models relating to pattern formation and morphogenesis inD. discoideumare discussed in light of these results.