Serum Oxytocin Levels and Logical Memory in Older People in Rural Japan
Serum Oxytocin Levels and Logical Memory in Older People in Rural Japan
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DOI：
10.1177/0891988720915526
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发表时间：
2020-04-01
影响因子：
2.6
通讯作者：
Monji, Akira
中科院分区：
文献类型：
--
作者：
Kunitake, Yutaka;Imamura, Yoshiomi;Monji, Akira
目的：本研究旨在调查日本农村老年人血清催产素 (OT) 与逻辑记忆之间的关系。方法：这是一项横断面研究，采用 2009 年 10 月至 2011 年 3 月进行的调查。大部分研究是日本全国痴呆症患病率调查的一部分。最终样本包括居住在日本农村的 385 名 65 岁或以上的社区居民。平均年龄和标准差为 75.7 +/- 6.76 岁（144 名男性，平均年龄 75.0 +/- 6.48 岁；241 名女性，平均年龄 76.2 +/- 6.91 岁）。参与者接受了痴呆症患病率调查的筛查检查。筛选检查包括简易精神状态检查、临床痴呆评级和韦克斯勒记忆量表修订版（WMSR）中的“逻辑记忆A”。我们使用 WMSR 逻辑记忆 II 延迟回忆评分 (LM II-DR) 来评估逻辑记忆。采用酶联免疫分析法测定血清OT水平。结果：女性血清OT水平显着高于男性。本研究通过多重线性回归分析表明，日本农村老年女性的血清 OT 水平与 LM II-DR 呈正相关。结论：目前的结果表明，日本农村老年女性的 OT 与逻辑记忆之间存在正相关。
Objective:The present study aimed to investigate the relationship between serum oxytocin (OT) and logical memory among older people in rural Japan.Methods:This was a cross-sectional study using a survey conducted from October 2009 through March 2011. Most of the study was conducted as part of a national prevalence survey of dementia in Japan. The final sample comprised 385 community-dwelling people aged 65 years or older living in rural Japan. The mean age and standard deviation were 75.7 +/- 6.76 years (144 men, mean age 75.0 +/- 6.48 years; 241 women, mean age 76.2 +/- 6.91 years). The participants underwent screening examinations for a prevalence survey of dementia. The screening examinations were the Mini-Mental State Examination, Clinical Dementia Rating, and "logical memory A" from the Wechsler Memory Scale-Revised (WMSR). We used the WMSR Logical Memory II delayed recall score (LM II-DR) to assess logical memory. Levels of serum OT were obtained using the enzyme immunoassay method.Results:Serum OT levels were significantly higher among women than men. The present study revealed that serum OT levels were positively associated with LM II-DR in older women living in rural Japan in multiple linear regression analyses.Conclusions:The present results suggested a positive correlation between OT and logical memory in older women living in rural Japan.