Evaluation of Rapid Urine Test for the Detection of Helicobacter pylori Infection in the Vietnamese Population
Evaluation of Rapid Urine Test for the Detection of Helicobacter pylori Infection in the Vietnamese Population
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DOI：
10.1007/s10620-009-0720-9
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发表时间：
2010-01-01
影响因子：
3.1
通讯作者：
Moriyama, Masatsugu
中科院分区：
文献类型：
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作者：
Nguyen, Lam Tung;Uchida, Tomohisa;Moriyama, Masatsugu
目的本研究试图评估RAPIRUN试验在越南人群中诊断幽门螺杆菌感染的价值。方法我们招募了148名接受上消化道内镜检查的越南患者，期间进行了5次胃活检；收集了每位患者的血液和尿液样本。幽门螺杆菌感染状态通过三种不同方法的组合来确定，包括培养、免疫组织化学和血清ELISA。使用尿液样本进行RAPIRUN测试。结果RAPIRUN检测在越南患者中的敏感性、特异性和准确性分别为79.5%、90.7%和84.5%。结论RAPIRUN检测具有特异性高、灵敏度可接受、无创、方便、快速等优点，可用于越南人群幽门螺杆菌感染的诊断。
Purpose This study attempted to assess the value of the RAPIRUN test for the diagnosis of Helicobacter pylori infection in the Vietnamese population. Methods We recruited 148 Vietnamese patients undergoing upper gastrointestinal endoscopy during which five gastric biopsies were taken; blood and urine samples were collected from each patient. Helicobacter pylori infection status was determined by a combination of three different methods, including culture, immunohistochemistry, and serum ELISA. RAPIRUN tests were performed using urine samples. Results The sensitivity, specificity, and accuracy of the RAPIRUN test in these Vietnamese patients were 79.5, 90.7, and 84.5%, respectively. Conclusions The RAPIRUN test is useful for the diagnosis of H. pylori infection in the Vietnamese population, showing high specificity, acceptable sensitivity, non-invasiveness, convenience, and rapidity.