The Relationships Between Preoperative Sexual Desire and Quality of Life Following Radical Prostatectomy: A 5-Year Follow-Up Study
The Relationships Between Preoperative Sexual Desire and Quality of Life Following Radical Prostatectomy: A 5-Year Follow-Up Study
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DOI：
10.1111/j.1743-6109.2012.02788.x
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发表时间：
2012-09-01
影响因子：
3.5
通讯作者：
Arai, Yoichi
中科院分区：
文献类型：
--
作者：
Namiki, Shunichi;Ishidoya, Shigeto;Arai, Yoichi
导论.关于性欲与根治性乳腺癌切除术之间关系的研究较少。目标。根据术前SD评估RP与生活质量（QOL）的关系。主要结果测量。使用简表36测量总体QOL。性功能和烦恼用加州大学洛杉矶前列腺癌指数（PCI）测量。采用PCI评价术后SD的变化。方法.我们分析了285例接受RP的男性患者的数据，这些患者前瞻性地入选了一项纵向队列研究。根据患者在基线时是否有SD，将其分为两组，这在PCI问卷中解决：低SD（LSD）组和高SD（HSD）组。在治疗前和RP后3、6、12、24和60个月完成评估。结果在244名男性中，52%在RP之前具有高或中等水平的SD，而48%报告其SD水平较低。HSD组在基线时的性功能和性困扰评分优于LSD组（均P <0.001）。51%的HSD组报告3个月时SD为差或非常差，在所有术后时间点均未恢复至术前水平。近20%的LSD组在RP后恢复了比基线水平更高的SD。HSD组在术后随访期间的性困扰评分均低于基线水平（P <0.001）。然而，与基线相比，LSD组在RP后表现出相同的性困扰评分。结论. RP对SD以及性功能和性困扰有不良影响。HSD患者术后对性功能障碍的痛苦大于LSD患者。Namiki S，Ishidoya S，Nakagawa H，Ito A，Kaiho Y，Tochigi T，Takegami M，and Arai Y.术前性欲与根治性膀胱切除术后生活质量的关系：5年随访研究。J Sex Med 2012; 9：24482456。
Introduction. There were few studies about the relationship between sexual desire (SD) and radical prostatectomy (RP). Aims. We assessed the relationships between RP and quality of life (QOL) according to the preoperative SD. Main Outcome Measure. General QOL was measured with Short Form 36. Sexual function and bother were measured with the University of California, Los Angeles Prostate Cancer Index (PCI). Changes of postoperative SD were also evaluated using PCI. Methods. We analyzed data from 285 men who underwent RP and were prospectively enrolled into a longitudinal cohort study. Patients were divided into two groups according to whether they had SD at baseline, which is addressed in the PCI questionnaire: a low SD (LSD) group and a high SD (HSD) group. The assessments were completed before treatment and 3, 6, 12, 24, and 60 months after RP. Results. Of the 244 men, 52% had high or a fair level of SD before RP, whereas 48% reported that the level of their SD was low. The HSD group reported better sexual function and sexual bother scores than the LSD group at baseline (both P < 0.001). Fifty-one percent of the HSD group reported that SD at 3 months was poor or very poor, which did not return to the preoperative level at all postoperative time points. Nearly 20% of the LSD group regained higher SD after RP than the baseline level. The HSD group showed worse sexual bother scores than the baseline throughout the postoperative follow-up (P < 0.001). However, the LSD group demonstrated equivalent sexual bother scores after RP compared with the baseline. Conclusions. RP adversely affected SD as well as sexual function and sexual bother. The patients who had HSD experienced greater distress concerning their sexual dysfunction postoperatively than those with LSD. Namiki S, Ishidoya S, Nakagawa H, Ito A, Kaiho Y, Tochigi T, Takegami M, and Arai Y. The relationships between preoperative sexual desire and quality of life following radical prostatectomy: A 5-year follow-up study. J Sex Med 2012;9:24482456.