Allometric scaling and growth: Evaluation and applications in subadult body mass estimation
Allometric scaling and growth: Evaluation and applications in subadult body mass estimation
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异速生长缩放和生长：亚成人体重估计的评估和应用
DOI：
10.1002/ajpa.24329
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发表时间：
2021
影响因子：
2.8
通讯作者：
Liu, Hon‐Man
中科院分区：
文献类型：
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作者：
Yim, An‐Di;Konigsberg, Lyle W.;Hwa, Hsiao‐Lin;Chang, Chin‐Chen;Chen, Jo‐Yu;Liu, Hon‐Man
目的先前开发的亚成人体质量估计方法尚未在欧洲裔美国人或非裔美国人以外的人群中进行测试。本研究以当代台湾人为样本，对这些方法进行验证。通过评估它们的准确性和偏差，我们讨论了亚成人体重估计中常用的身体质量和骨骼特征之间的异速生长关系是否在不同人群中保留。材料和方法来自台湾大学医院0-17岁 男女个体的计算机断层扫描和记录的体重。直接从扫描或从重建的三维模型中收集面积的极第二矩、股骨远端干骺端宽度和最大上/下股骨头直径。结果目前的方法能较好地估测台湾人的体重，其精确度和偏差与其他验证研究报告的结果相似。所有方法的误差都有随年龄增长而增加的趋势。减缩长轴回归表明，不同骨骼性状和不同年龄组体质量之间的异速生长关系都可以用一条共同的拟合线来概括。讨论结果表明，体重和不同骨骼特征之间的异速生长关系在种群间基本是保守的。经修订的方法提供了更好的适用性，具有强有力的基本理论理由，并有可能在未来进行改进。
ObjectivesPreviously developed methods in subadult body mass estimation have not been tested in populations other than European–American or African–American. This study uses a contemporary Taiwanese sample to test these methods. Through evaluating their accuracy and bias, we addressed whether the allometric relationships between body mass and skeletal traits commonly used in subadult body mass estimation are conserved among different populations.Materials and MethodsComputed tomography scans of lower limbs from individuals aged 0–17 years old of both sexes were collected from National Taiwan University Hospital along with documented body weight. Polar second moment of area, distal femoral metaphyseal breadth, and maximum superior/inferior femoral head diameter were collected either directly from the scans or from reconstructed 3D models. Estimated body mass was compared with documented body mass to assess the performance of the equations.ResultsCurrent methods provided good body mass estimates in Taiwanese individuals, with accuracy and bias similar to those reported in other validation studies. A tendency for increasing error with increasing age was observed for all methods. Reduced major axis regression showed the allometric relationships between different skeletal traits and body mass across different age categories can all be summarized using a common fitted line. A revised, maximum likelihood‐based approach was proposed for all skeletal traits.DiscussionThe results suggested that the allometric relationships between body mass and different skeletal traits are largely conserved among populations. The revised method provided improved applicability with strong underlying theoretical justifications, and potential for future improvements.