A Highly Active Ruthenium(II) Pyrazolyl–Pyridyl–Pyrazole Complex Catalyst for Transfer Hydrogenation of Ketones
A Highly Active Ruthenium(II) Pyrazolyl–Pyridyl–Pyrazole Complex Catalyst for Transfer Hydrogenation of Ketones
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DOI：
10.1021/om300602w
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发表时间：
2012-07
期刊：
影响因子：
2.8
通讯作者：
Weiwei Jin;Liandi Wang;Zhengkun Yu
中科院分区：
文献类型：
--
作者：
Weiwei Jin;Liandi Wang;Zhengkun Yu
合成了含吡唑基-吡啶-吡唑配体的Ru(II)配合物，对回流异丙醇中酮的转移加氢反应表现出极高的催化活性，最终的反应时间可达720000h-1。配体中吡唑臂上的β-NH官能团对反应速度有显著的加速作用。配体的非对称性(半对称性)和可转化的NH基团的存在归因于络合催化剂的高催化活性。
Ruthenium(II) complexes bearing a pyrazolyl–pyridyl–pyrazole ligand were synthesized and exhibited exceptionally high catalytic activity in the transfer hydrogenation of ketones in refluxing isopropyl alcohol, reaching final TOFs up to 720 000 h–1. The β-NH functionality of the pyrazole arm in the ligand demonstrated a remarkable acceleration effect on the reaction rate. The unsymmetrical nature (hemilability) and presence of the convertible NH group of the ligand is attributed to the high catalytic activity of the complex catalyst.