Tactile information from the vibrissal system modulates hippocampal functioning.
Tactile information from the vibrissal system modulates hippocampal functioning.
复制标题
来自振动系统的触觉信息调节海马功能。
DOI：
10.1016/j.crneur.2022.100034
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
González-Pérez,Óscar
中科院分区：
文献类型：
--
作者：
Ibarra-Castañeda,Nereida;Moy-Lopez,NormaA;González-Pérez,Óscar
大多数哺乳动物都有感觉触觉毛，也称为胡须或触须。传统上，胡须与各种生存技能有关，包括触觉辨别，距离评估，食物获取，间隙跨越和社会互动。触须的功能在躯体感觉皮层（通常称为桶皮层）中进行处理。因此，大多数与胡须相关的研究都集中在这个皮层区域。然而，越来越多的证据表明，触须系统调节海马生理的几个方面。这一图形审查的目的是总结累积的证据表明，胡须调节神经功能和细胞在几个海马亚领域。有趣的是，胡须的缺乏显着影响神经元放电在CA1和CA3海马子字段，改变空间映射，损害导航技能，修改细胞结构，并减少成年神经发生在齿状回。这一证据扩展了我们对胡须与海马功能相关性的理解，并为探索海马中胡须功能与神经可塑性之间的新关联提供了见解。
Most mammals have sensory tactile hairs, also known as whiskers or vibrissae. Traditionally, whiskers are associated with diverse survival skills, including tactile discrimination, distance assessment, food acquisition, gap crossing, and social interaction. Vibrissae functions are processed in the somatosensorial cortex, commonly referred to as the barrel cortex. Hence, most of the whisker-related research has been focused on this cortical region. However, increasing evidence indicates that the vibrissal system modulates several aspects of hippocampal physiology. This graphical review aims to summarize cumulative evidence indicating that whiskers regulate the neural function and cellularity in several hippocampal subfields. Interestingly, lack of whiskers notably affects neuronal firing in CA1 and CA3 hippocampal subfields, alters spatial mapping, impairs navigational skills, modifies cytoarchitecture, and reduces the adult neurogenesis in the dentate gyrus. This evidence extends our understanding of how whiskers are related to hippocampal function and offers insights to explore novel associations between whisker functions and neural plasticity in the hippocampus.