Genetics: Mitotic chromosomal anomalies among 1210 infertile men
Genetics: Mitotic chromosomal anomalies among 1210 infertile men
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遗传学：1210 名不育男性的有丝分裂染色体异常
DOI：
10.1093/oxfordjournals.humrep.a019178
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发表时间：
1996
影响因子：
6.1
通讯作者：
A. Jequier
中科院分区：
文献类型：
--
作者：
N. Pandiyan;A. Jequier
详细的医疗和临床检查进行了1608名男子参加不孕症诊所，以确定是否有任何表现出异常的精液也有任何其他容易识别的临床条件。根据世界卫生组织的标准，总共有1210名男性表现出异常的精液图。对这1210名男性的白色血细胞进行核型分析，发现44名（3.6%）个体存在常染色体或性染色体畸变。然而，没有一个单一的特征，他们的精液图或临床条件是任何诊断价值，以预测存在的染色体异常。
Detailed medical and clinical examinations were carried out on 1608 men attending an infertility clinic to determine if any of those exhibiting abnormal semenograms also had any other readily identifiable clinical condition. In all, 1210 men showed abnormal semenograms according to World Health Organization criteria. Karyotyping of the white blood cells in these 1210 men revealed 44 (3.6%) individuals with either autosomal or sex chromosomal aberrations. However, no single characteristic feature of their semeno-gram or clinical condition was of any diagnostic value to predict the existence of a chromosomal anomaly.