A PRODUCTION OF AMINO ACIDS UNDER POSSIBLE PRIMITIVE EARTH CONDITIONS
A PRODUCTION OF AMINO ACIDS UNDER POSSIBLE PRIMITIVE EARTH CONDITIONS
复制标题
DOI：
10.1126/science.117.3046.528
复制
发表时间：
1953-01-01
期刊：
影响因子：
56.9
通讯作者：
MILLER, SL
中科院分区：
文献类型：
--
作者：
MILLER, SL
氨基酸的生产--在化合物的压力作用下（5）.在另一种方法中，将材料沿基线沿着8 cm而不是作为点施加到纸上，并且在解析之后，从纸上切下含有各种化合物的8 x 5 cm区域，并将其卷在带壳小瓶中。然后将10只麻醉的家蝇引入每个小瓶中，并通过击倒率和24小时死亡率来表征化合物的毒性。纸色谱法可用于研究磷杀虫剂在植物、哺乳动物和昆虫体内的代谢。例如，有了它，我们已经能够证明双硫磷及其甲基类似物转化为。美洲大蠊（Periplaneta americana（L.）（二）、进一步的研究正在进行中。该方法在研究热对纯化的对硫磷和甲基对硫磷的作用、分离形成的化合物和研究其生物学特性方面也很有价值（1）。
A Production ofAmino Acids Under ties of the comiipounds manometrically (5). In the other, the material is applied to the paper along 8 cm of the base line rather than as a spot and, after resolu-tion, areas 8 x 5 cm containing the various compounds are cut from the paper and rolled in shell vials. Ten anesthetized houseflies are then introduced into each vial, and the toxicity of the compounds is character-ized by rate of knockdown and 24-hr mlortality. The paper chromatographic method is useful in studying the metabolism of phosphorus insecticides in plants, mamimals, and insects. With it, for example, we have been able to demonstrate the conversion of parathion and its methyl analog to. the corresponding phosphates by an enzyme system found in Periplaneta americana (L.)(2). Further studies are in progress. The method has also been of value in studying the action of heat on purified parathion-and methyl para-thion and in isolating the compounds formed and in studying their biological properties (1).