New phylogenomic and comparative analyses provide corroborating evidence that Myxozoa is Cnidaria
New phylogenomic and comparative analyses provide corroborating evidence that Myxozoa is Cnidaria
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新的系统发育和比较分析提供了确凿的证据表明粘液动物是刺胞动物
DOI：
10.1016/j.ympev.2014.08.016
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发表时间：
2014-12-01
影响因子：
4.1
通讯作者：
Miao, Wei
中科院分区：
文献类型：
--
作者：
Feng, Jin-Mei;Xiong, Jie;Miao, Wei
粘虫是一种形态简单的寄生虫，在水产养殖中造成了巨大的经济损失。尽管有积极的研究，但粘虫的系统发育位置仍然模糊不清。在获得粘虫Thelohanellus kitauei的基因组和转录组数据后，我们从三个不同的角度研究了粘虫的系统发育位置。首先，新测序的基因组数据的基因组分析强烈支持粘虫的单系性，粘虫是刺胞动物门内水母虫的姐妹。其次，我们在T. kitauei基因组中的小胶原蛋白具有与刺胞动物特异性小胶原蛋白相似的分子特征，表明T. kitauei可能具有类似于刺胞动物的功能，粘虫是刺胞动物。此外，系统发育分析表明，在粘动物和水母动物的小胶原有一个共同的祖先。第三，我们检测了T. kitauei基因组的序列，这些序列也存在于刺胞动物Hydra magnipillatata中，表明粘虫属属于刺胞动物门。因此，我们的研究结果有力地支持粘虫作为一个派生的刺胞动物类群与水母类的亲和力，有助于了解刺胞动物的形态，发育和生活史的多样性及其演变。(C)2014爱思唯尔公司All rights reserved.
Myxozoa, a diverse group of morphologically simplified endoparasites, are well known fish parasites causing substantial economic losses in aquaculture. Despite active research, the phylogenetic position of Myxozoa remains ambiguous. After obtaining the genome and transcriptome data of the myxozoan Thelohanellus kitauei, we examined the phylogenetic position of Myxozoa from three different perspectives. First, phylogenomic analyses with the newly sequenced genomic data strongly supported the monophyly of Myxozoa and that Myxozoa is sister to Medusozoa within Cnidaria. Second, we detected two homologs to cnidarian-specific minicollagens in the T. kitauei genome with molecular characteristics similar to cnidarian-specific minicollagens, suggesting that the minicollagen homologs in T. kitauei may have functions similar to those in Cnidaria and that Myxozoa is Cnidaria. Additionally, phylogenetic analyses revealed that the minicollagens in myxozoans and medusozoans have a common ancestor. Third, we detected 11 of the 19 proto-mesodermal genes in the T. kitauei genome, which were also present in the cnidarian Hydra magnipapillata, indicating Myxozoa is within Cnidaria. Thus, our results robustly support Myxozoa as a derived cnidarian taxon with an affinity to Medusozoa, helping to understand the diversity of the morphology, development and life cycle of Cnidaria and its evolution. (C) 2014 Elsevier Inc. All rights reserved.