Relating the steady-state visual evoked potential to single-stimulus responses derived from m-sequence stimulation
Relating the steady-state visual evoked potential to single-stimulus responses derived from m-sequence stimulation
复制标题
DOI：
10.1007/s10633-015-9492-z
复制
发表时间：
2015-08-01
影响因子：
1.4
通讯作者：
Bach, Michael
中科院分区：
文献类型：
--
作者：
Heinrich, Sven P.;Groten, Maresa;Bach, Michael
目的 稳态视觉诱发电位有多种应用，包括客观敏锐度测试。然而，大约一半的受试者在中间空间频率处出现非单调的空间频率调谐（“凹口”）。一个可能的原因在于单刺激反应的时间叠加。对 20 名受试者进行了调查。方法通过对 m 序列刺激的反应进行解卷积来估计对棋盘起始的单刺激反应。在此基础上，通过时间重叠的单刺激反应的叠加来预测稳态反应，并与正常记录的进行比较。结果预测和记录的稳态响应之间的一致性在受试者之间差异很大，从良好的匹配（包括调谐曲线的非单调特征）到显着的偏差。结论我们的数据与时间叠加一致，解释了检查尺寸调谐曲线的个体间可变部分，而不是其主要决定因素。
Purpose Steady-state visual evoked potentials have various applications, including objective acuity testing. However, a non-monotonous spatial-frequency tuning (a "notch'') occurs at intermediate spatial frequencies in about half of the examinees. One possible reason lies in the temporal superposition of single-stimulus responses. This was investigated in 20 subjects. Methods Single-stimulus responses to checkerboard onsets were estimated through deconvolution of responses to m-sequence stimulation. Based on these, steady-state responses were predicted through super-position of temporally overlapping single-stimulus responses and compared to normally recorded steady-state responses. Discrepancies were analyzed in both the time and frequency domains. Results The agreement between predicted and recorded steady-state responses varied greatly among subjects, ranging from a good match including non-monotonous features of the tuning curve to substantial deviations. Although in some subjects the tuning of the recorded responses was better matched by the predicted responses than by the deconvolved m-sequence responses from which the prediction was computed, the correlation was not significantly different at the group level. In most subjects, there was only a small to moderate contribution of higher harmonics. The match between predicted and recorded responses was not always uniform across electrode locations. Conclusions Our data are consistent with temporal superposition explaining an interindividually variable part of the checksize tuning curve without being its primary determinant.