Specific wetting probed with biomimetic emulsion droplets
Specific wetting probed with biomimetic emulsion droplets
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DOI：
10.1039/b806635c
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发表时间：
2008-01-01
期刊：
影响因子：
3.4
通讯作者：
Bibette, Jerome
中科院分区：
文献类型：
--
作者：
Fattaccioli, Jacques;Baudry, Jean;Bibette, Jerome
We have produced emulsion droplets of controlled size and composition coated by ligands, and studied the adhesion of these drops on a solid substrate coated by receptors and polymers. Using transmission, RICM and fluorescence microscopy we assess the size, contact angle and ligand density for each drop. We first show that non-specific interactions significantly enhance the proteins density within the adhesive patch. Then we show that binding within the patch is partially inhibited in good agreement with the hypothesis of an absence of translational diffusion. We confirm that the density of specific bonds sets the adhesive energy and therefore the final contact angle, and finally show that specific binding in our system is always associated with the existence of a positive line tension, which linearly increases with the density of receptors. These experiments describe a new scenario for specific wetting which raises the importance of the coupling between non-specific interactions and specific binding.
