The impact of place and time on the proportion of late-stage diagnosis: the case of prostate cancer in Florida, 1981-2007.
The impact of place and time on the proportion of late-stage diagnosis: the case of prostate cancer in Florida, 1981-2007.
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DOI：
10.1016/j.sste.2012.03.001
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发表时间：
2012-09
影响因子：
3.4
通讯作者：
Xiao H
中科院分区：
文献类型：
--
作者：
Goovaerts P;Xiao H
介绍了一套用于健康结果时间序列地理差异探索性空间数据分析的技术，包括时间和地理空间相结合的三维显示技术、用于噪声滤波的二项克里格技术、用于检测相邻地理单元之间显著差异的时空边界分析技术以及用于对具有相似时间趋势的单元进行分组的空间加权聚类分析技术。该方法用于探索佛罗里达州年度县级晚期前列腺癌诊断比例的时间序列差异。自1981年以来，该州晚期诊断的平均比例下降了50%。这种下降始于20世纪90年代初，当时前列腺特异性抗原（PSA）检测广泛普及，佛罗里达州的一些地区经历了快速城市化。边界分析显示，筛查程序的影响存在地域差异，特别是在筛查程序开始提供时。随着时间的推移，各县之间的差距正在缩小，除了大本德地区，那里的下降速度要慢得多。
A suite of techniques is introduced for the exploratory spatial data analysis of geographical disparities in time series of health outcomes, including 3D display in a combined time and geography space, binomial kriging for noise filtering, space-time boundary analysis to detect significant differences between adjacent geographical units, and spatially-weighted cluster analysis to group units with similar temporal trends. The approach is used to explore how time series of annual county-level proportions of late-stage prostate cancer diagnosis differ across Florida. The state-average proportion of late-stage diagnosis decreased 50% since 1981. This drop started in the early 1990s when prostate-specific antigen (PSA) test became widely available and several parts of Florida underwent fast urbanization. Boundary analysis revealed geographical disparities in the impact of the screening procedure, in particular as it began available. The gap among counties is narrowing with time, except for the Big Bend region where the decline is much slower.