Simultaneous pain intensity rating and quantification of ischemia throughout exercise and recovery in proximal versus distal arterial claudication
Simultaneous pain intensity rating and quantification of ischemia throughout exercise and recovery in proximal versus distal arterial claudication
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DOI：
10.1177/1358863x17734304
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发表时间：
2017-12-01
影响因子：
3.5
通讯作者：
Henni, Samir
中科院分区：
文献类型：
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作者：
Fouasson-Chailloux, Alban;Abraham, Pierre;Henni, Samir
同时血流动力学的变化和疼痛等级的估计，而行走动脉跛行的数据是缺乏的。本研究旨在确定在近端或远端跛行中，疼痛出现时（PAINapp）、最大疼痛（PAINmax）和疼痛缓解（PAINrel）的近端和远端定位之间是否存在经皮氧分压（tcpO 2）差异，以及tcpO 2变化与疼痛强度之间是否存在关系。我们分析了下肢缺血的疼痛评分（视觉模拟量表（VAS）），在小腿（n = 41）或小腿（n = 19）跛行患者的恒定负荷平板运动试验期间，通过与静息氧压（DROP）tcpO 2指数的降低进行测量。采用ANOVA检验分析小牛与臀部的结果。计算个体VAS与DROP之间的R-2相关系数。缺血强度与疼痛等级变化相关。疼痛的出现需要明显的缺血，但尽管缺血持续，疼痛消失了。我们观察到近端或远端跛行在PAINapp、PAINmax或PAINrel时的DROP无统计学差异。疼痛评分与DROP之间存在显著相关性：从PAINapp到PAINmax，R-2 = 0.750（小腿）和0.829（臀部），从PAINmax到PAINrel，R-2 = 0.608（小腿）和0.560（臀部）; p
Data on simultaneous hemodynamic changes and pain rating estimation in arterial claudication while walking are lacking. This study was conducted to determine if a difference in transcutaneous oxygen pressure (tcpO2) exists between proximal and distal localization at pain appearance (PAINapp), maximal pain (PAINmax) and pain relief (PAINrel) in proximal or distal claudication and if a relationship exists between tcpO2 changes and pain intensity. We analyzed the pain rating (Visual Analog Scale (VAS)) to lower limb ischemia, measured with the decrease from rest of oxygen pressure (DROP) tcpO2 index during constant-load treadmill tests in patients with calf (n = 41) or buttock (n = 19) claudication. Calves versus buttocks results were analyzed with ANOVA tests. The R-2 correlation coefficient between individual VAS versus DROP was calculated. Ischemia intensity versus pain rating changes were correlated. Significant ischemia was required for pain appearance, but pain disappeared despite the persistence of ischemia. We observed no statistical difference for DROP at PAINapp, PAINmax or PAINrel between proximal or distal claudication. A significant correlation between pain rating versus DROP was found: from PAINapp to PAINmax, R-2 = 0.750 (calves) and 0.829 (buttocks), and from PAINmax to PAINrel, R-2 = 0.608 (calves) and 0.560 (buttocks); p