L-theanine - a unique amino acid of green tea and its relaxation effect in humans
L-theanine - a unique amino acid of green tea and its relaxation effect in humans
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DOI：
10.1016/s0924-2244(99)00044-8
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发表时间：
1999-06-01
影响因子：
15.3
通讯作者：
Yokogoshi, H
中科院分区：
文献类型：
--
作者：
Juneja, LR;Chu, DC;Yokogoshi, H
自古以来，人们就说喝绿茶能使人放松。产生放松感的物质是茶氨酸。茶氨酸是一种独特的氨基酸，几乎只存在于茶树中，是“绿茶”具有异国情调的主要成分。经腹腔注射的l -茶氨酸在30分钟内到达大脑，没有任何代谢变化。茶氨酸还作为大脑中的神经递质，在高血压大鼠中显著降低血压。一般来说，动物总是在大脑表面产生非常微弱的电脉冲，称为脑电波。脑电波根据精神状态分为四种类型，即α波、β波、δ波和θ波。α波的产生被认为是松弛的一个指标。在人类志愿者中，口服茶氨酸（50-200毫克）后40分钟内在大脑表面的枕部和顶叶区域产生ar波，表明放松而不引起嗜睡。随着l -茶氨酸的成功工业生产，我们现在能够供应太阳茶氨酸（TM） （l -茶氨酸的商品名称），这为设计以放松和减轻压力为目标的食品和医疗食品提供了巨大的机会。日本Taiyo Kagaku Co., Ltd .因开发太阳茶氨酸（TM）在欧洲食品配料展（法兰克福）上获得1998年“食品配料研究奖”。评委们认为这是一项记录详尽、引人入胜的研究。(C) 1999 Elsevier Science Ltd.出版版权所有。
Since ancient times, it has been said that drinking green tea brings relaxation. The substance that is responsible for a sense of relaxation, is theanine. Theanine is a unique amino acid found almost solely in tea plants and the main component responsible for the exotic taste of 'green' tea. It was found that L-theanine administered intraperitoneally to rats reached the brain within 30 min without any metabolic change. Theanine also acts as a neurotransmitter in the brain and decreased blood pressure significantly in hypertensive rats. In general, animals always generate very weak electric pulses on the surface of the brain, called brain waves. Brain waves are classified into four types, namely alpha, beta, delta and theta-waves, based on mental conditions. Generation of alpha-waves is considered to be an index of relaxation. In human volunteers, ar-waves were generated on the occipital and parietal regions of the brain surface within 40 min after the oral administration of theanine (50-200 mg), signifying relaxation without causing drowsiness. With the successful industrial production of L-theanine, we are now able to supply Suntheanine(TM) (trade name of L-theanine) which offers a tremendous opportunity for designing foods and medical foods targeting relaxation and the reduction of stress. Taiyo Kagaku Co., Ltd, Japan won the 1998 'Food Ingredient Research Award' for development of Suntheanine(TM) at Food Ingredients in Europe (Frankfurt). The judges felt it was a particularly well-documented and fascinating piece of research. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.