BURNING MOUTH SYNDROME
BURNING MOUTH SYNDROME
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DOI：
10.1111/j.1365-4362.1995.tb00617.x
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发表时间：
1995-07-01
影响因子：
3.6
通讯作者：
STENGEL, FM
中科院分区：
文献类型：
--
作者：
GRINSPAN, D;BLANCO, GF;STENGEL, FM
背景和目标。灼口综合征（EMS）是一种常见的过程，产生显着的口腔感觉障碍症状。其发病机制和诊断存在争议。治疗效果不令人满意。本研究的目的是：（1）分析一个可能的协议的定义EMS;（2）分析其原因;（3）提出一个治疗方案，已被证明是非常有效的，在我们的经验，并没有以前被证实。500例BMS患者采用专门为这种疾病设计的研究方案进行了回顾性评价。有局部或全身疾病过程可能导致继发性无症状口腔疼痛的患者被排除在研究之外。大多数接受评估的患者是60岁以上的女性，有口腔症状，包括持续数月或数年的灼热感和疼痛，以及多次治疗失败的病史。患者表现出与焦虑相关的抑郁，并有家族精神障碍的证据。根据这些发现，并排除可能模拟这种综合征的口腔疼痛症状，我们诊断为真正的或基本的心身性EMS。用于治疗这些神经症的疗法并不总是有用的。反苯环丙胺联合小剂量抗焦虑药和催眠药以及口腔科医生的心理治疗是最有效的治疗方法。EMS应定义为导致口腔感觉迟钝数月或数年的心身过程。
Background and Objectives. Burning mouth syndrome (EMS) is a frequent process that produces marked oral dysesthetic symptoms. There is controversy over its etiopathogenesis and diagnosis. Therapeutic results are unsatisfactory. The objectives of this study were: (1) to analyze a possible agreement on the definition of EMS; (2) to analyze its cause; (3) to propose a therapeutic scheme that has been shown to be highly effective in our experience and has not been previously reported.Methods. Five hundred patients with symptomatology of BMS were retrospectively evaluated with a study protocol, specially designed for this disease. Patients with local or general disease processes that could cause secondary asymptomatic stomatodynia were excluded from the study.Results. Most of the patients evaluated were women over 60 years of age with oral symptoms, including a sensation of heat and burning, and pain, lasting for months or years, and a history of multiple unsuccessful treatments. The patients showed depression associated with anxiety, with evidence of psychiatric disorders in the family. Based on these findings and eliminating symptomatic painful conditions of the mouth that may simulate this syndrome, we diagnosed a genuine or basic EMS Of psychosomatic origin. Therapies used in the treatment of these neurotic conditions were not always useful. Tranylcypromine associated with anxiolytics and hypnotics in low doses plus the support of psychotherapy by the stomatologist were the most effective treatments.Conclusions. The EMS should be defined as a psychosomatic process causing oral dysesthesias for months or years.