Continuous-flow fast atom bombardment mass spectrometry
Continuous-flow fast atom bombardment mass spectrometry
复制标题
连续流快速原子轰击质谱分析
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
R. Caprioli
中科院分区：
文献类型：
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作者：
R. Caprioli
快速原子轰击（FAB）质谱法对分析生物化学产生了巨大的影响，为生物化学家和分子生物学家解决结构问题开辟了新的途径。虽然FAB已经被广泛使用，并且比其他质谱电离技术有许多优点，但很明显，该技术的几个缺点严重限制了它的应用。通常，这些困难是由于该技术中使用了高浓度的甘油或其他有机液体支撑基质。
Fast atom bombardment (FAB) mass spectrometry has made an enormous impact on analytical biochemistry, opening up new approaches to the biochemist and molecular biologist for the solution of structural problems. Although FAB has become widely used and has many advantages over other mass spectrometric ionization techniques, it is clear that several disadvantages of the technique severely limit its utility. Generally, these difficulties are a consequence of the high concentration of glycerol or other organic liquid support matrix used in the technique.