Cerebral sparganosis in children: epidemiological, clinical and MR imaging characteristics.
Cerebral sparganosis in children: epidemiological, clinical and MR imaging characteristics.
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儿童脑裂头蚴病：流行病学、临床和磁共振成像特征
DOI：
10.1186/1471-2431-12-155
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发表时间：
2012-09-24
期刊：
影响因子：
2.4
通讯作者：
Hou BL
中科院分区：
文献类型：
--
作者：
Gong C;Liao W;Chineah A;Wang X;Hou BL
研究背景小儿脑裂头蚴病是一种极为罕见的中枢神经系统疾病，由迭宫绦虫属绦虫幼虫引起。本文对18例经病理、血清学及MRI检查证实的脑裂头蚴病患儿的流行病学、临床及MRI特点进行了回顾性分析，并对其进行了总结。结果18例患儿共发现27个病灶，其中12例为多发性病灶，12例为多发性病灶。12例患者的12个病灶为单发病灶，其余6例患者的病灶为多发且不对称。病变部位：额叶7例，顶叶11例，颞叶4例，枕叶2例，基底节1例，小脑半球1例，桥脑1例。病灶在T1加权像上呈轻度低信号，在T2加权像上呈中度高信号，伴病灶周围脑实质水肿。患者行钆喷酸葡胺盐增强扫描，影像学表现为异常强化，表现为周边环形、串珠状或蛇形管状强化。后续的MR扫描进行了8例，和三个八例暴露迁移和形状的变化的病变areas. ConclusionsThe MR介绍在我们的研究中一般是相似的，在以前的研究。然而，在以往的文献中，并没有关于病变的蛇形管状和逗号状增强的报道。增强扫描和血清学检查阳性的随访是诊断儿童脑裂头蚴病的重要方法。
BackgroundCerebral sparganosis in children is an extremely rare disease of central nervous system, and caused by a tapeworm larva from the genus of Spirometra. In this study, we discussed and summarized epidemiological, clinical and MR imaging characteristics of eighteen children with cerebral sparganosis for a better diagnosis and treatment of the disease.MethodsEighteen children with cerebral sparganosis verified by pathology, serological tests and MR presentations were retrospectively investigated, and the epidemiologic and clinical characteristics of the disease were studied.ResultsTwenty-seven lesions were found in the eighteen children. Twelve lesions in twelve patients were solitary while the lesions in the rest six patients were multiple and asymmetrical. The positions of the lesions were: seven in frontal, eleven in parietal, four in temporal and two in occipital lobes, one in basal ganglia, one in cerebella hemisphere and one in pons. The lesions were presented as slight hypointensity on T1-weighted images but moderate hyperintensity on T2-weighted images with perilesional brain parenchyma edema. Enhanced MR scans by using Gadopentetic Acid Dimeglumine Salt were performed in the patients, and the images demonstrated abnormal enhancements with the patterns of a peripheral ring, or a tortuous beaded, or a serpiginous tubular shape. Follow-up MR scans were preformed for eight patients, and three out of the eight cases exposed migrations and changes in shapes of the lesion areas.ConclusionsThe MR presentations in our study in general were similar to those in previous studies. However serpiginous tubular and comma-shaped enhancements of lesions have not been previously reported. The enhanced MR imaging and follow-up MR scans with the positive results from serological tests are the most important methods for the clinical diagnosis of cerebral sparganosis in children.
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影响因子：
3.5
作者：
Song, T.;Wang, W.-S.;Zhou, F.
通讯作者：
Zhou, F.
影响因子：
19.7
作者：
MOON, WK;CHANG, KH;HAN, MC
通讯作者：
HAN, MC
影响因子：
2.6
作者：
Chiu, C-H;Chiou, T-L;Yen, P-S
通讯作者：
Yen, P-S
影响因子：
--
作者：
KIM H;KIM S-I;CHO S-Y
通讯作者：
CHO S-Y
影响因子：
4.1
作者：
Deng, Lei;Xiong, Pengju;Qian, Suokai
通讯作者：
Qian, Suokai