Characterization of Neisseria gonorrhoeae strains with decreased susceptibility to fluoroquinolones isolated in Greece from 1996 to 1999
Characterization of Neisseria gonorrhoeae strains with decreased susceptibility to fluoroquinolones isolated in Greece from 1996 to 1999
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DOI：
10.1128/jcm.38.9.3489-3491.2000
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发表时间：
2000-09-01
影响因子：
9.4
通讯作者：
Tzelepi, E
中科院分区：
文献类型：
--
作者：
Mavroidi, A;Tzouvelekis, LS;Tzelepi, E
1996年至1999年在希腊分离的331株淋球菌菌株中，39株（11.8%）因gyrA和parC突变而对喹诺酮类药物的敏感性降低。常规分型和脉冲场凝胶电泳结果表明，其中34个菌株与克隆相关。流行病学资料表明，流行性克隆在一组高频传播者中持续存在。
Of the 331 Neisseria gonorrhoeae strains isolated in Greece from 1996 to 1999, 39 (11.8%) exhibited decreased susceptibility to quinolones due to gyrA and parC mutations. Conventional typing and pulsed-field gel electrophoresis showed that 34 of these isolates were clonally related. Epidemiological data indicated that the epidemic clone was sustained in a group of high-frequency transmitters.