What is the Incidence of Biliary Carcinoma in Choledochal Cysts, When Do They Develop, and How Should it Affect Management?
What is the Incidence of Biliary Carcinoma in Choledochal Cysts, When Do They Develop, and How Should it Affect Management?
复制标题
DOI：
10.1007/s00268-014-2831-5
复制
发表时间：
2015-02-01
影响因子：
2.6
通讯作者：
Cooperman, Avram M.
中科院分区：
文献类型：
--
作者：
Sastry, Amit V.;Abbadessa, Benjamin;Cooperman, Avram M.
计算成人胆总管囊肿（CC）中癌症的发病率，以确定手术的时机和需要。在78篇出版物（1996-2010）中，5780例报告的CC患者中有434例患有癌症。胆管癌（70.4%）和胆囊癌（23.5%）是最常见的恶性肿瘤.只有9例恶性肿瘤在18岁之前报告（0.42%）。相比之下，成人恶性肿瘤的发病率为11.4%。诊断癌症的中位年龄为42岁，发病率每十年增加一次。
The incidence of cancer in choledochal cysts (CCs) in adults was calculated to determine the timing and need for surgery. In 78 publications (1996-2010), 434 of 5780 reported CCs patients had cancer. Cholangiocarcinoma (70.4 %) and gallbladder cancer (23.5 %) were the most common malignancies. Only nine malignancies were reported before age 18 (0.42 %). In contrast, the incidence of malignancy in adults was 11.4 %. The median age for diagnosis of cancer was 42 years, and the incidence increased with each decade.