Response inhibition in Veterans with a history of mild traumatic brain injury: The role of self-reported complaints in objective performance.
Response inhibition in Veterans with a history of mild traumatic brain injury: The role of self-reported complaints in objective performance.
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有轻度创伤性脑损伤史的退伍军人的反应抑制：自我报告的抱怨在客观表现中的作用。
DOI：
10.1080/13803395.2020.1776847
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发表时间：
2020
影响因子：
2.2
通讯作者：
Schiehser,DawnM
中科院分区：
文献类型：
--
作者：
Holiday,KelseyA;Clark,AlexandraL;Merritt,VictoriaC;Nakhla,MarinaZ;Sorg,Scott;Delano-Wood,Lisa;Schiehser,DawnM
引言虽然在轻度创伤性脑损伤（mTBI）的平民中检测到了反应抑制（RI）的客观缺陷，但目前尚不清楚尽管自我报告的去抑制普遍存在，但客观RI是否在患有mTBI的退伍军人中更糟。评估退伍军人的RI是至关重要的，因为他们独特的特点，包括战斗和爆炸暴露，除了精神病合并症的患病率。因此，我们认为，本研究的目的是（1）检查患有mTBI的退伍军人与非mTBI的退伍军人相比的RI表现，和（2）比较具有和不具有自我报告的抑制解除投诉的明确定义的mTBI退伍军人亚组与非mTBI退伍军人的RI表现。方法53名mTBI退伍军人和37名非mTBI退伍军人完成Go/No-Go RI任务和自我报告的抑制解除测量（额叶系统行为量表）和精神症状。情绪和人口统计学协变的ANCOVA将非mTBI退伍军人的RI表现与（1）mTBI退伍军人的总样本（n= 53）和（2）mTBI退伍军人的RI表现进行了比较。（t评分≥ 60; mTBI-SubjDis;n= 23）和低（t-评分< 60; mTBI-NoSubjDis; n= 30）水平的自我报告disinhibitation.ResultsThere之间的mTBI组作为一个整体和非mTBI退伍军人组RI没有显着差异。然而，当将mTBI退伍军人按其解除抑制的临床显著性问题分组时，mTBI-SubjDis组表现出比mTBI-NoSubjDis和非mTBI退伍军人组显著更差的RI。RI性能之间没有显着差异，观察mTBI-NoSubjDis和非mTBI退伍军人groups.ConclusionsResults表明，mTBI退伍军人与自我报告的抑制水平升高显示RI的客观措施，独立的情绪性能下降。研究结果强调了主观抱怨对mTBI执行功能的独特贡献，并强调了评估认知抱怨的重要性，以便识别那些最有可能出现长期不良结果的人。
IntroductionAlthough objective deficits in response inhibition (RI) have been detected in civilians with mild traumatic brain injury (mTBI), it remains unclear whether objective RI is worse in military Veterans with mTBI despite the prevalence of self-reported disinhibition. Assessing RI in Veterans is critical due to their unique characteristics, including combat and blast exposure, in addition to the prevalence of psychiatric comorbidity. Therefore, the aims of this study were to (1) examine RI performance in Veterans with mTBI compared to non-mTBI Veterans and (2) compare RI performance in well-defined subgroups of mTBI Veterans with and without self-reported complaints of disinhibition to non-mTBI Veterans.Method53 mTBI Veterans and 37 non-mTBI Veterans completed a Go/No-Go RI task and measures of self-reported disinhibition (Frontal Systems Behavior Scale) and psychiatric symptoms. ANCOVAs covarying for mood and demographics compared RI performances of the non-mTBI Veterans to (1) the total sample of mTBI Veterans (n= 53) and to (2) mTBI Veterans with elevated (t-score ≥ 60; mTBI-SubjDis;n= 23) and low (t-score < 60; mTBI-NoSubjDis;n= 30) levels of self-reported disinhibition.ResultsThere were no significant differences in RI between the mTBI group as a whole and the non-mTBI Veterans group. However, when Veterans with mTBI were divided into groups by clinically-significant concern about their disinhibition, the mTBI-SubjDis group demonstrated significantly worse RI than the mTBI-NoSubjDis and non-mTBI Veteran groups. No significant differences in RI performance were observed between the mTBI-NoSubjDis and non-mTBI Veteran groups.ConclusionsResults indicate that mTBI Veterans with elevated levels of self-reported disinhibition show diminished performance on objective measures of RI, independent of mood. Findings highlight the unique contribution of subjective complaints on executive functioning in mTBI, and they underscore the importance of assessing cognitive complaints in order to identify those most at risk for poor-long term outcomes.